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Combined Inhibition of DYRK1A, SMAD, and Trithorax Pathways Synergizes to Induce Robust Replication in Adult Human Beta Cells.
Wang P, Karakose E, Liu H, Swartz E, Ackeifi C, Zlatanic V, Wilson J, González BJ, Bender A, Takane KK, Ye L, Harb G, Pagliuca F, Homann D, Egli D, Argmann C, Scott DK, Garcia-Ocaña A, Stewart AF. Wang P, et al. Among authors: homann d. Cell Metab. 2019 Mar 5;29(3):638-652.e5. doi: 10.1016/j.cmet.2018.12.005. Epub 2018 Dec 20. Cell Metab. 2019. PMID: 30581122 Free PMC article.
GLP-1 receptor agonists synergize with DYRK1A inhibitors to potentiate functional human β cell regeneration.
Ackeifi C, Wang P, Karakose E, Manning Fox JE, González BJ, Liu H, Wilson J, Swartz E, Berrouet C, Li Y, Kumar K, MacDonald PE, Sanchez R, Thorens B, DeVita R, Homann D, Egli D, Scott DK, Garcia-Ocaña A, Stewart AF. Ackeifi C, et al. Among authors: homann d. Sci Transl Med. 2020 Feb 12;12(530):eaaw9996. doi: 10.1126/scitranslmed.aaw9996. Sci Transl Med. 2020. PMID: 32051230 Free PMC article.
Limited extent and consequences of pancreatic SARS-CoV-2 infection.
van der Heide V, Jangra S, Cohen P, Rathnasinghe R, Aslam S, Aydillo T, Geanon D, Handler D, Kelley G, Lee B, Rahman A, Dawson T, Qi J, D'Souza D, Kim-Schulze S, Panzer JK, Caicedo A, Kusmartseva I, Posgai AL, Atkinson MA, Albrecht RA, García-Sastre A, Rosenberg BR, Schotsaert M, Homann D. van der Heide V, et al. Among authors: homann d. Cell Rep. 2022 Mar 15;38(11):110508. doi: 10.1016/j.celrep.2022.110508. Epub 2022 Feb 21. Cell Rep. 2022. PMID: 35247306 Free PMC article.
Maladaptive positive feedback production of ChREBPβ underlies glucotoxic β-cell failure.
Katz LS, Brill G, Zhang P, Kumar A, Baumel-Alterzon S, Honig LB, Gómez-Banoy N, Karakose E, Tanase M, Doridot L, Alvarsson A, Davenport B, Wang P, Lambertini L, Stanley SA, Homann D, Stewart AF, Lo JC, Herman MA, Garcia-Ocaña A, Scott DK. Katz LS, et al. Among authors: homann d. Nat Commun. 2022 Jul 30;13(1):4423. doi: 10.1038/s41467-022-32162-x. Nat Commun. 2022. PMID: 35908073 Free PMC article.
Author Correction: Maladaptive positive feedback production of ChREBPβ underlies glucotoxic β-cell failure.
Katz LS, Brill G, Zhang P, Kumar A, Baumel-Alterzon S, Honig LB, Gómez-Banoy N, Karakose E, Tanase M, Doridot L, Alvarsson A, Davenport B, Wang P, Lambertini L, Stanley SA, Homann D, Stewart AF, Lo JC, Herman MA, Garcia-Ocaña A, Scott DK. Katz LS, et al. Among authors: homann d. Nat Commun. 2022 Sep 27;13(1):5681. doi: 10.1038/s41467-022-33243-7. Nat Commun. 2022. PMID: 36167859 Free PMC article. No abstract available.
Expression of SARS-CoV-2 Entry Factors in the Pancreas of Normal Organ Donors and Individuals with COVID-19.
Kusmartseva I, Wu W, Syed F, Van Der Heide V, Jorgensen M, Joseph P, Tang X, Candelario-Jalil E, Yang C, Nick H, Harbert JL, Posgai AL, Paulsen JD, Lloyd R, Cechin S, Pugliese A, Campbell-Thompson M, Vander Heide RS, Evans-Molina C, Homann D, Atkinson MA. Kusmartseva I, et al. Among authors: homann d. Cell Metab. 2020 Dec 1;32(6):1041-1051.e6. doi: 10.1016/j.cmet.2020.11.005. Epub 2020 Nov 13. Cell Metab. 2020. PMID: 33207244 Free PMC article.
100 results