Chapman RN - Search Results

1

Streptococcal dTDP-L-rhamnose biosynthesis enzymes: functional characterization and lead compound identification.

van der Beek SL, Zorzoli A, Çanak E, Chapman RN, Lucas K, Meyer BH, Evangelopoulos D, de Carvalho LPS, Boons GJ, Dorfmueller HC, van Sorge NM. van der Beek SL, et al. Among authors: chapman rn. Mol Microbiol. 2019 Apr;111(4):951-964. doi: 10.1111/mmi.14197. Epub 2019 Jan 31. Mol Microbiol. 2019. PMID: 30600561 Free PMC article.

2

GacA is essential for Group A Streptococcus and defines a new class of monomeric dTDP-4-dehydrorhamnose reductases (RmlD).

van der Beek SL, Le Breton Y, Ferenbach AT, Chapman RN, van Aalten DM, Navratilova I, Boons GJ, McIver KS, van Sorge NM, Dorfmueller HC. van der Beek SL, et al. Among authors: chapman rn. Mol Microbiol. 2015 Dec;98(5):946-62. doi: 10.1111/mmi.13169. Epub 2015 Oct 1. Mol Microbiol. 2015. PMID: 26278404 Free PMC article.

3

4,6- O-Pyruvyl Ketal Modified N-Acetylmannosamine of the Secondary Cell Wall Polysaccharide of Bacillus anthracis Is the Anchoring Residue for Its Surface Layer Proteins.

Chapman RN, Liu L, Boons GJ. Chapman RN, et al. J Am Chem Soc. 2018 Dec 12;140(49):17079-17085. doi: 10.1021/jacs.8b08857. Epub 2018 Nov 30. J Am Chem Soc. 2018. PMID: 30452253

4

Molecular Basis for the Attachment of S-Layer Proteins to the Cell Wall of Bacillus anthracis.

Sychantha D, Chapman RN, Bamford NC, Boons GJ, Howell PL, Clarke AJ. Sychantha D, et al. Among authors: chapman rn. Biochemistry. 2018 Apr 3;57(13):1949-1953. doi: 10.1021/acs.biochem.8b00060. Epub 2018 Mar 14. Biochemistry. 2018. PMID: 29522326

5

PatB1 is an O-acetyltransferase that decorates secondary cell wall polysaccharides.

Sychantha D, Little DJ, Chapman RN, Boons GJ, Robinson H, Howell PL, Clarke AJ. Sychantha D, et al. Among authors: chapman rn. Nat Chem Biol. 2018 Jan;14(1):79-85. doi: 10.1038/nchembio.2509. Epub 2017 Oct 30. Nat Chem Biol. 2018. PMID: 29083419

6

Inhibition of hypoxia inducible factor 1-transcription coactivator interaction by a hydrogen bond surrogate alpha-helix.

Henchey LK, Kushal S, Dubey R, Chapman RN, Olenyuk BZ, Arora PS. Henchey LK, et al. Among authors: chapman rn. J Am Chem Soc. 2010 Jan 27;132(3):941-3. doi: 10.1021/ja9082864. J Am Chem Soc. 2010. PMID: 20041650 Free PMC article.

7

Optimized synthesis of hydrogen-bond surrogate helices: surprising effects of microwave heating on the activity of Grubbs catalysts.

Chapman RN, Arora PS. Chapman RN, et al. Org Lett. 2006 Dec 7;8(25):5825-8. doi: 10.1021/ol062443z. Org Lett. 2006. PMID: 17134282 Free PMC article.

8

Solid-phase synthesis of hydrogen-bond surrogate-derived alpha-helices.

Dimartino G, Wang D, Chapman RN, Arora PS. Dimartino G, et al. Among authors: chapman rn. Org Lett. 2005 Jun 9;7(12):2389-92. doi: 10.1021/ol0506516. Org Lett. 2005. PMID: 15932205

9

A highly stable short alpha-helix constrained by a main-chain hydrogen-bond surrogate.

Chapman RN, Dimartino G, Arora PS. Chapman RN, et al. J Am Chem Soc. 2004 Oct 6;126(39):12252-3. doi: 10.1021/ja0466659. J Am Chem Soc. 2004. PMID: 15453743

10

Testosterone phenyl propionate (TPP): biological trials with a new androgen.

DEKANSKI J, CHAPMAN RN. DEKANSKI J, et al. Among authors: chapman rn. Br J Pharmacol Chemother. 1953 Sep;8(3):271-7. doi: 10.1111/j.1476-5381.1953.tb00793.x. Br J Pharmacol Chemother. 1953. PMID: 13093945 Free PMC article. No abstract available.

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