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Page 1
Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes⁻4.
Mangoni AA, Guillou C, Vanden Eynde JJ, Hulme C, Jampilek J, Li W, Prokai-Tatrai K, Rautio J, Collina S, Tuccinardi T, Sousa ME, Sabatier JM, Galdiero S, Karaman R, Kokotos G, Torri G, Luque FJ, Vasconcelos MH, Hadjipavlou-Litina D, Siciliano C, Gütschow M, Ragno R, Gomes PAC, Agrofoglio LA, Muñoz-Torrero D. Mangoni AA, et al. Among authors: luque fj. Molecules. 2018 Dec 31;24(1):130. doi: 10.3390/molecules24010130. Molecules. 2018. PMID: 30602690 Free PMC article.
Tacrine-based dual binding site acetylcholinesterase inhibitors as potential disease-modifying anti-Alzheimer drug candidates.
Camps P, Formosa X, Galdeano C, Gómez T, Muñoz-Torrero D, Ramírez L, Viayna E, Gómez E, Isambert N, Lavilla R, Badia A, Clos MV, Bartolini M, Mancini F, Andrisano V, Bidon-Chanal A, Huertas O, Dafni T, Luque FJ. Camps P, et al. Among authors: luque fj. Chem Biol Interact. 2010 Sep 6;187(1-3):411-5. doi: 10.1016/j.cbi.2010.02.013. Epub 2010 Feb 16. Chem Biol Interact. 2010. PMID: 20167211
Tetrahydrobenzo[h][1,6]naphthyridine-6-chlorotacrine hybrids as a new family of anti-Alzheimer agents targeting β-amyloid, tau, and cholinesterase pathologies.
Di Pietro O, Pérez-Areales FJ, Juárez-Jiménez J, Espargaró A, Clos MV, Pérez B, Lavilla R, Sabaté R, Luque FJ, Muñoz-Torrero D. Di Pietro O, et al. Among authors: luque fj. Eur J Med Chem. 2014 Sep 12;84:107-17. doi: 10.1016/j.ejmech.2014.07.021. Epub 2014 Jul 7. Eur J Med Chem. 2014. PMID: 25016233
Shogaol-huprine hybrids: dual antioxidant and anticholinesterase agents with β-amyloid and tau anti-aggregating properties.
Pérez-Areales FJ, Di Pietro O, Espargaró A, Vallverdú-Queralt A, Galdeano C, Ragusa IM, Viayna E, Guillou C, Clos MV, Pérez B, Sabaté R, Lamuela-Raventós RM, Luque FJ, Muñoz-Torrero D. Pérez-Areales FJ, et al. Among authors: luque fj. Bioorg Med Chem. 2014 Oct 1;22(19):5298-307. doi: 10.1016/j.bmc.2014.07.053. Epub 2014 Aug 7. Bioorg Med Chem. 2014. PMID: 25156301
Design, synthesis and biological evaluation of N-methyl-N-[(1,2,3-triazol-4-yl)alkyl]propargylamines as novel monoamine oxidase B inhibitors.
Di Pietro O, Alencar N, Esteban G, Viayna E, Szałaj N, Vázquez J, Juárez-Jiménez J, Sola I, Pérez B, Solé M, Unzeta M, Muñoz-Torrero D, Luque FJ. Di Pietro O, et al. Among authors: luque fj. Bioorg Med Chem. 2016 Oct 15;24(20):4835-4854. doi: 10.1016/j.bmc.2016.06.045. Epub 2016 Jun 28. Bioorg Med Chem. 2016. PMID: 27396685
Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes.
Muñoz-Torrero D, Mangoni AA, Guillou C, Collina S, Vanden Eynde JJ, Rautio J, Keserű GM, Hulme C, Chibale K, Luque FJ, Karaman R, Gütschow M, Liu H, Ragno R. Muñoz-Torrero D, et al. Among authors: luque fj. Molecules. 2017 May 5;22(5):743. doi: 10.3390/molecules22050743. Molecules. 2017. PMID: 28475136 Free PMC article.
274 results