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Survival factor NFIL3 restricts FOXO-induced gene expression in cancer.
Keniry M, Pires MM, Mense S, Lefebvre C, Gan B, Justiano K, Lau YK, Hopkins B, Hodakoski C, Koujak S, Toole J, Fenton F, Calahan A, Califano A, DePinho RA, Maurer M, Parsons R. Keniry M, et al. Genes Dev. 2013 Apr 15;27(8):916-27. doi: 10.1101/gad.214049.113. Genes Dev. 2013. PMID: 23630076 Free PMC article.
A secreted PTEN phosphatase that enters cells to alter signaling and survival.
Hopkins BD, Fine B, Steinbach N, Dendy M, Rapp Z, Shaw J, Pappas K, Yu JS, Hodakoski C, Mense S, Klein J, Pegno S, Sulis ML, Goldstein H, Amendolara B, Lei L, Maurer M, Bruce J, Canoll P, Hibshoosh H, Parsons R. Hopkins BD, et al. Science. 2013 Jul 26;341(6144):399-402. doi: 10.1126/science.1234907. Epub 2013 Jun 6. Science. 2013. PMID: 23744781 Free PMC article.
PTEN function: the long and the short of it.
Hopkins BD, Hodakoski C, Barrows D, Mense SM, Parsons RE. Hopkins BD, et al. Trends Biochem Sci. 2014 Apr;39(4):183-90. doi: 10.1016/j.tibs.2014.02.006. Epub 2014 Mar 18. Trends Biochem Sci. 2014. PMID: 24656806 Free PMC article. Review.
Analysis of intracellular PTEN signaling and secretion.
Hodakoski C, Fine B, Hopkins B, Parsons R. Hodakoski C, et al. Methods. 2015 May;77-78:164-71. doi: 10.1016/j.ymeth.2014.11.008. Epub 2014 Nov 15. Methods. 2015. PMID: 25462559 Free PMC article. Review.
Obesity and Cancer Mechanisms: Cancer Metabolism.
Hopkins BD, Goncalves MD, Cantley LC. Hopkins BD, et al. J Clin Oncol. 2016 Dec 10;34(35):4277-4283. doi: 10.1200/JCO.2016.67.9712. Epub 2016 Nov 7. J Clin Oncol. 2016. PMID: 27903152 Free PMC article. Review.
Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine.
Pauli C, Hopkins BD, Prandi D, Shaw R, Fedrizzi T, Sboner A, Sailer V, Augello M, Puca L, Rosati R, McNary TJ, Churakova Y, Cheung C, Triscott J, Pisapia D, Rao R, Mosquera JM, Robinson B, Faltas BM, Emerling BE, Gadi VK, Bernard B, Elemento O, Beltran H, Demichelis F, Kemp CJ, Grandori C, Cantley LC, Rubin MA. Pauli C, et al. Among authors: hopkins bd. Cancer Discov. 2017 May;7(5):462-477. doi: 10.1158/2159-8290.CD-16-1154. Epub 2017 Mar 22. Cancer Discov. 2017. PMID: 28331002 Free PMC article.
60 results