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Nanoparticles targeting extra domain B of fibronectin-specific to the atherosclerotic lesion types III, IV, and V-enhance plaque detection and cargo delivery.
Yu M, Ortega CA, Si K, Molinaro R, Schoen FJ, Leitao RFC, Xu X, Mahmoudi M, Ahn S, Liu J, Saw PE, Lee IH, Brayner MMB, Lotfi A, Shi J, Libby P, Jon S, Farokhzad OC. Yu M, et al. Theranostics. 2018 Nov 15;8(21):6008-6024. doi: 10.7150/thno.24365. eCollection 2018. Theranostics. 2018. PMID: 30613278 Free PMC article.
Targeted Nanotherapeutics Encapsulating Liver X Receptor Agonist GW3965 Enhance Antiatherogenic Effects without Adverse Effects on Hepatic Lipid Metabolism in Ldlr-/- Mice.
Yu M, Amengual J, Menon A, Kamaly N, Zhou F, Xu X, Saw PE, Lee SJ, Si K, Ortega CA, Choi WI, Lee IH, Bdour Y, Shi J, Mahmoudi M, Jon S, Fisher EA, Farokhzad OC. Yu M, et al. Adv Healthc Mater. 2017 Oct;6(20):10.1002/adhm.201700313. doi: 10.1002/adhm.201700313. Epub 2017 Jul 21. Adv Healthc Mater. 2017. PMID: 28730752 Free PMC article.
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