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Generation and characterization of antagonistic anti-human interleukin (IL)-18 monoclonal antibodies with high affinity: Two types of monoclonal antibodies against full-length IL-18 and the neoepitope of inflammatory caspase-cleaved active IL-18.
Nariai Y, Kamino H, Obayashi E, Kato H, Sakashita G, Sugiura T, Migita K, Koga T, Kawakami A, Sakamoto K, Kadomatsu K, Nakakido M, Tsumoto K, Urano T. Nariai Y, et al. Among authors: nakakido m. Arch Biochem Biophys. 2019 Mar 15;663:71-82. doi: 10.1016/j.abb.2019.01.001. Epub 2019 Jan 4. Arch Biochem Biophys. 2019. PMID: 30615852 Free article.
Affinity improvement of a therapeutic antibody by structure-based computational design: generation of electrostatic interactions in the transition state stabilizes the antibody-antigen complex.
Kiyoshi M, Caaveiro JM, Miura E, Nagatoishi S, Nakakido M, Soga S, Shirai H, Kawabata S, Tsumoto K. Kiyoshi M, et al. Among authors: nakakido m. PLoS One. 2014 Jan 27;9(1):e87099. doi: 10.1371/journal.pone.0087099. eCollection 2014. PLoS One. 2014. PMID: 24475232 Free PMC article.
79 results