Bao G - Search Results

1

A Self-Deleting AAV-CRISPR System for In Vivo Genome Editing.

Li A, Lee CM, Hurley AE, Jarrett KE, De Giorgi M, Lu W, Balderrama KS, Doerfler AM, Deshmukh H, Ray A, Bao G, Lagor WR. Li A, et al. Among authors: bao g. Mol Ther Methods Clin Dev. 2018 Dec 6;12:111-122. doi: 10.1016/j.omtm.2018.11.009. eCollection 2019 Mar 15. Mol Ther Methods Clin Dev. 2018. PMID: 30619914 Free PMC article.

2

CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences.

Lin Y, Cradick TJ, Brown MT, Deshmukh H, Ranjan P, Sarode N, Wile BM, Vertino PM, Stewart FJ, Bao G. Lin Y, et al. Among authors: bao g. Nucleic Acids Res. 2014 Jun;42(11):7473-85. doi: 10.1093/nar/gku402. Epub 2014 May 16. Nucleic Acids Res. 2014. PMID: 24838573 Free PMC article.

3

COSMID: A Web-based Tool for Identifying and Validating CRISPR/Cas Off-target Sites.

Cradick TJ, Qiu P, Lee CM, Fine EJ, Bao G. Cradick TJ, et al. Among authors: bao g. Mol Ther Nucleic Acids. 2014 Dec 2;3(12):e214. doi: 10.1038/mtna.2014.64. Mol Ther Nucleic Acids. 2014. PMID: 25462530 Free PMC article.

4

Trans-spliced Cas9 allows cleavage of HBB and CCR5 genes in human cells using compact expression cassettes.

Fine EJ, Appleton CM, White DE, Brown MT, Deshmukh H, Kemp ML, Bao G. Fine EJ, et al. Among authors: bao g. Sci Rep. 2015 Jul 1;5:10777. doi: 10.1038/srep10777. Sci Rep. 2015. PMID: 26126518 Free PMC article.

5

Efficient fdCas9 Synthetic Endonuclease with Improved Specificity for Precise Genome Engineering.

Aouida M, Eid A, Ali Z, Cradick T, Lee C, Deshmukh H, Atef A, AbuSamra D, Gadhoum SZ, Merzaban J, Bao G, Mahfouz M. Aouida M, et al. Among authors: bao g. PLoS One. 2015 Jul 30;10(7):e0133373. doi: 10.1371/journal.pone.0133373. eCollection 2015. PLoS One. 2015. PMID: 26225561 Free PMC article.

6

Controlled delivery of β-globin-targeting TALENs and CRISPR/Cas9 into mammalian cells for genome editing using microinjection.

Cottle RN, Lee CM, Archer D, Bao G. Cottle RN, et al. Among authors: bao g. Sci Rep. 2015 Nov 12;5:16031. doi: 10.1038/srep16031. Sci Rep. 2015. PMID: 26558999 Free PMC article.

7

Streptococcus thermophilus CRISPR-Cas9 Systems Enable Specific Editing of the Human Genome.

Müller M, Lee CM, Gasiunas G, Davis TH, Cradick TJ, Siksnys V, Bao G, Cathomen T, Mussolino C. Müller M, et al. Among authors: bao g. Mol Ther. 2016 Mar;24(3):636-44. doi: 10.1038/mt.2015.218. Epub 2015 Dec 14. Mol Ther. 2016. PMID: 26658966 Free PMC article.

8

Nuclease Target Site Selection for Maximizing On-target Activity and Minimizing Off-target Effects in Genome Editing.

Lee CM, Cradick TJ, Fine EJ, Bao G. Lee CM, et al. Among authors: bao g. Mol Ther. 2016 Mar;24(3):475-87. doi: 10.1038/mt.2016.1. Epub 2016 Jan 11. Mol Ther. 2016. PMID: 26750397 Free PMC article. Review.

9

The Neisseria meningitidis CRISPR-Cas9 System Enables Specific Genome Editing in Mammalian Cells.

Lee CM, Cradick TJ, Bao G. Lee CM, et al. Among authors: bao g. Mol Ther. 2016 Mar;24(3):645-54. doi: 10.1038/mt.2016.8. Epub 2016 Jan 19. Mol Ther. 2016. PMID: 26782639 Free PMC article.

10

A Burden of Rare Variants Associated with Extremes of Gene Expression in Human Peripheral Blood.

Zhao J, Akinsanmi I, Arafat D, Cradick TJ, Lee CM, Banskota S, Marigorta UM, Bao G, Gibson G. Zhao J, et al. Among authors: bao g. Am J Hum Genet. 2016 Feb 4;98(2):299-309. doi: 10.1016/j.ajhg.2015.12.023. Am J Hum Genet. 2016. PMID: 26849112 Free PMC article.

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