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Page 1
Polyunsaturated fatty acid metabolites: biosynthesis in Leishmania and role in parasite/host interaction.
Paloque L, Perez-Berezo T, Abot A, Dalloux-Chioccioli J, Bourgeade-Delmas S, Le Faouder P, Pujo J, Teste MA, François JM, Schebb NH, Mainka M, Rolland C, Blanpied C, Dietrich G, Bertrand-Michel J, Deraison C, Valentin A, Cenac N. Paloque L, et al. J Lipid Res. 2019 Mar;60(3):636-647. doi: 10.1194/jlr.M091736. Epub 2019 Jan 9. J Lipid Res. 2019. PMID: 30626624 Free PMC article.
Antileishmanial pharmacomodulation in 8-nitroquinolin-2(1H)-one series.
Kieffer C, Cohen A, Verhaeghe P, Paloque L, Hutter S, Castera-Ducros C, Laget M, Rault S, Valentin A, Rathelot P, Azas N, Vanelle P. Kieffer C, et al. Among authors: paloque l. Bioorg Med Chem. 2015 May 15;23(10):2377-86. doi: 10.1016/j.bmc.2015.03.064. Epub 2015 Mar 31. Bioorg Med Chem. 2015. PMID: 25846065
Novel 8-nitroquinolin-2(1H)-ones as NTR-bioactivated antikinetoplastid molecules: Synthesis, electrochemical and SAR study.
Pedron J, Boudot C, Hutter S, Bourgeade-Delmas S, Stigliani JL, Sournia-Saquet A, Moreau A, Boutet-Robinet E, Paloque L, Mothes E, Laget M, Vendier L, Pratviel G, Wyllie S, Fairlamb A, Azas N, Courtioux B, Valentin A, Verhaeghe P. Pedron J, et al. Among authors: paloque l. Eur J Med Chem. 2018 Jul 15;155:135-152. doi: 10.1016/j.ejmech.2018.06.001. Epub 2018 Jun 5. Eur J Med Chem. 2018. PMID: 29885575 Free PMC article.
Antitrypanosomatid Pharmacomodulation at Position 3 of the 8-Nitroquinolin-2(1H)-one Scaffold Using Palladium-Catalysed Cross-Coupling Reactions.
Pedron J, Boudot C, Bourgeade-Delmas S, Sournia-Saquet A, Paloque L, Rastegari M, Abdoulaye M, El-Kashef H, Bonduelle C, Pratviel G, Wyllie S, Fairlamb AH, Courtioux B, Verhaeghe P, Valentin A. Pedron J, et al. Among authors: paloque l. ChemMedChem. 2018 Oct 22;13(20):2217-2228. doi: 10.1002/cmdc.201800456. Epub 2018 Sep 17. ChemMedChem. 2018. PMID: 30221468 Free PMC article.
Discovery of new thienopyrimidinone derivatives displaying antimalarial properties toward both erythrocytic and hepatic stages of Plasmodium.
Cohen A, Suzanne P, Lancelot JC, Verhaeghe P, Lesnard A, Basmaciyan L, Hutter S, Laget M, Dumètre A, Paloque L, Deharo E, Crozet MD, Rathelot P, Dallemagne P, Lorthiois A, Sibley CH, Vanelle P, Valentin A, Mazier D, Rault S, Azas N. Cohen A, et al. Among authors: paloque l. Eur J Med Chem. 2015 May 5;95:16-28. doi: 10.1016/j.ejmech.2015.03.011. Epub 2015 Mar 10. Eur J Med Chem. 2015. PMID: 25791675
Evaluation of antiplasmodial and antileishmanial activities of herbal medicine Pseudelephantopus spiralis (Less.) Cronquist and isolated hirsutinolide-type sesquiterpenoids.
Girardi C, Fabre N, Paloque L, Ramadani AP, Benoit-Vical F, González-Aspajo G, Haddad M, Rengifo E, Jullian V. Girardi C, et al. Among authors: paloque l. J Ethnopharmacol. 2015 Jul 21;170:167-74. doi: 10.1016/j.jep.2015.05.014. Epub 2015 May 14. J Ethnopharmacol. 2015. PMID: 25980423
Discovery of a new antileishmanial hit in 8-nitroquinoline series.
Paloque L, Verhaeghe P, Casanova M, Castera-Ducros C, Dumètre A, Mbatchi L, Hutter S, Kraiem-M'rabet M, Laget M, Remusat V, Rault S, Rathelot P, Azas N, Vanelle P. Paloque L, et al. Eur J Med Chem. 2012 Aug;54:75-86. doi: 10.1016/j.ejmech.2012.04.029. Epub 2012 May 2. Eur J Med Chem. 2012. PMID: 22608675
Targeting the human parasite Leishmania donovani: discovery of a new promising anti-infectious pharmacophore in 3-nitroimidazo[1,2-a]pyridine series.
Castera-Ducros C, Paloque L, Verhaeghe P, Casanova M, Cantelli C, Hutter S, Tanguy F, Laget M, Remusat V, Cohen A, Crozet MD, Rathelot P, Azas N, Vanelle P. Castera-Ducros C, et al. Among authors: paloque l. Bioorg Med Chem. 2013 Nov 15;21(22):7155-64. doi: 10.1016/j.bmc.2013.09.002. Epub 2013 Sep 11. Bioorg Med Chem. 2013. PMID: 24080103
35 results