Wang N - Search Results

1

Identification of novel uracil derivatives incorporating benzoic acid moieties as highly potent Dipeptidyl Peptidase-IV inhibitors.

Huang J, Deng X, Zhou S, Wang N, Qin Y, Meng L, Li G, Xiong Y, Fan Y, Guo L, Lan D, Xing J, Jiang W, Li Q. Huang J, et al. Among authors: wang n. Bioorg Med Chem. 2019 Feb 15;27(4):644-654. doi: 10.1016/j.bmc.2019.01.001. Epub 2019 Jan 4. Bioorg Med Chem. 2019. PMID: 30642693

2

Design, synthesis, and protein methyltransferase activity of a unique set of constrained amine containing compounds.

Zhou H, Che X, Bao G, Wang N, Peng L, Barnash KD, Frye SV, James LI, Bai X. Zhou H, et al. Among authors: wang n. Bioorg Med Chem Lett. 2016 Sep 15;26(18):4436-4440. doi: 10.1016/j.bmcl.2016.08.004. Epub 2016 Aug 3. Bioorg Med Chem Lett. 2016. PMID: 27528434 Free PMC article.

3

Rapid generation of novel benzoic acid-based xanthine derivatives as highly potent, selective and long acting DPP-4 inhibitors: Scaffold-hopping and prodrug study.

Li Q, Meng L, Zhou S, Deng X, Wang N, Ji Y, Peng Y, Xing J, Yao G. Li Q, et al. Among authors: wang n. Eur J Med Chem. 2019 Oct 15;180:509-523. doi: 10.1016/j.ejmech.2019.07.045. Epub 2019 Jul 16. Eur J Med Chem. 2019. PMID: 31336309

4

Optimization of the benzamide fragment targeting the S₂' site leads to potent dipeptidyl peptidase-IV inhibitors.

Deng X, Wang N, Meng L, Zhou S, Huang J, Xing J, He L, Jiang W, Li Q. Deng X, et al. Among authors: wang n. Bioorg Chem. 2020 Jan;94:103366. doi: 10.1016/j.bioorg.2019.103366. Epub 2019 Oct 15. Bioorg Chem. 2020. PMID: 31640932

5

Corrigendum to "Optimization of the benzamide fragment targeting the S₂' site leads to potent dipeptidyl Peptidase-IV inhibitors" [Bioorg. Chem. 94 (2020) 103366].

Deng X, Wang N, Meng L, Zhou S, Huang J, Xing J, He L, Jiang W, Li Q. Deng X, et al. Among authors: wang n. Bioorg Chem. 2020 Jul;100:103898. doi: 10.1016/j.bioorg.2020.103898. Epub 2020 May 20. Bioorg Chem. 2020. PMID: 32416556 No abstract available.

6

The protective effects of natural product tunicatachalcone against neuroinflammation via targeting RIPK2 in microglia BV-2 cells stimulated by LPS.

Wen R, Lv J, Jia P, Yang W, Wang N, Wu X, Xue Z, Liu Y. Wen R, et al. Among authors: wang n. Bioorg Med Chem. 2022 Sep 1;69:116916. doi: 10.1016/j.bmc.2022.116916. Epub 2022 Jul 2. Bioorg Med Chem. 2022. PMID: 35792403

7

Exploration of novel hexahydropyrrolo[1,2-e]imidazol-1-one derivatives as antiviral agents against ZIKV and USUV.

Chen R, Francese R, Wang N, Li F, Sun X, Xu B, Liu J, Liu Z, Donalisio M, Lembo D, Zhou GC. Chen R, et al. Among authors: wang n. Eur J Med Chem. 2023 Feb 15;248:115081. doi: 10.1016/j.ejmech.2022.115081. Epub 2023 Jan 3. Eur J Med Chem. 2023. PMID: 36623328

8

Structure-Based Design of Novel G-Protein-Coupled Receptor TAAR1 Agonists as Potential Antipsychotic Drug Candidates.

Zhou Z, Zhang W, Zhao F, Sun Y, Wang N, Cheng J, Zhan P, Yang F, Sun JP, Liu X, Kang D. Zhou Z, et al. Among authors: wang n. J Med Chem. 2024 Mar 14;67(5):4234-4249. doi: 10.1021/acs.jmedchem.4c00195. Epub 2024 Feb 28. J Med Chem. 2024. PMID: 38416116

9

Discovery of Novel Aryl Triazolone Dihydropyridines (ATDPs) Targeting Highly Conserved Residue W229 as Promising HIV-1 NNRTIs.

Sun Y, Zhou Z, Wang N, Zhao F, Liu Y, Xu X, Wang X, Gou Z, De Clercq E, Pannecouque C, Zhan P, Kang D, Liu X. Sun Y, et al. Among authors: wang x, wang n. J Med Chem. 2024 Apr 25;67(8):6570-6584. doi: 10.1021/acs.jmedchem.4c00026. Epub 2024 Apr 13. J Med Chem. 2024. PMID: 38613773

10

Discovery of 2,4,6-trisubstituted pyrimidine derivatives as novel potent HIV-1 NNRTIs by exploiting the tolerant region II of the NNIBP.

Zhou Z, Sun Y, Qin Y, Wang N, Zhao F, Wang Z, Clercq E, Pannecouque C, Zhan P, Kang D, Liu X. Zhou Z, et al. Among authors: wang z, wang n. Eur J Med Chem. 2024 Nov 5;277:116708. doi: 10.1016/j.ejmech.2024.116708. Epub 2024 Jul 27. Eur J Med Chem. 2024. PMID: 39094273

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