Xing J - Search Results

1

Identification of novel uracil derivatives incorporating benzoic acid moieties as highly potent Dipeptidyl Peptidase-IV inhibitors.

Huang J, Deng X, Zhou S, Wang N, Qin Y, Meng L, Li G, Xiong Y, Fan Y, Guo L, Lan D, Xing J, Jiang W, Li Q. Huang J, et al. Among authors: xing j. Bioorg Med Chem. 2019 Feb 15;27(4):644-654. doi: 10.1016/j.bmc.2019.01.001. Epub 2019 Jan 4. Bioorg Med Chem. 2019. PMID: 30642693

2

Identification of dipeptidyl peptidase IV inhibitors: virtual screening, synthesis and biological evaluation.

Xing J, Li Q, Zhang S, Liu H, Zhao L, Cheng H, Zhang Y, Zhou J, Zhang H. Xing J, et al. Chem Biol Drug Des. 2014 Sep;84(3):364-77. doi: 10.1111/cbdd.12327. Epub 2014 May 14. Chem Biol Drug Des. 2014. PMID: 24674599

3

Design, synthesis, antibacterial evaluation and docking study of novel 2-hydroxy-3-(nitroimidazolyl)-propyl-derived quinolone.

Li Q, Xing J, Cheng H, Wang H, Wang J, Wang S, Zhou J, Zhang H. Li Q, et al. Among authors: xing j. Chem Biol Drug Des. 2015 Jan;85(1):79-90. doi: 10.1111/cbdd.12395. Epub 2014 Aug 16. Chem Biol Drug Des. 2015. PMID: 25048811

4

Discovery of Novel 2-(piperidin-4-yl)-1H-benzo[d]imidazole Derivatives as Potential Anti-Inflammatory Agents.

Li Q, Hu Q, Wang X, Zong Y, Zhao L, Xing J, Zhou J, Zhang H. Li Q, et al. Among authors: xing j. Chem Biol Drug Des. 2015 Oct;86(4):509-16. doi: 10.1111/cbdd.12513. Epub 2015 Mar 16. Chem Biol Drug Des. 2015. PMID: 25588891

5

Identification of anthranilamide derivatives as potential factor Xa inhibitors: drug design, synthesis and biological evaluation.

Xing J, Yang L, Li H, Li Q, Zhao L, Wang X, Zhang Y, Zhou M, Zhou J, Zhang H. Xing J, et al. Eur J Med Chem. 2015 May 5;95:388-99. doi: 10.1016/j.ejmech.2015.03.052. Epub 2015 Mar 25. Eur J Med Chem. 2015. PMID: 25839438

6

Synthesis and biological evaluation of GPR40/FFAR1 agonists containing 3,5-dimethylisoxazole.

Yang L, Zhang J, Si L, Han L, Zhang B, Ma H, Xing J, Zhao L, Zhou J, Zhang H. Yang L, et al. Among authors: xing j. Eur J Med Chem. 2016 Jun 30;116:46-58. doi: 10.1016/j.ejmech.2016.03.054. Epub 2016 Mar 25. Eur J Med Chem. 2016. PMID: 27054485

7

Design, synthesis and biological evaluation of novel 2,3-dihydroquinazolin- 4(1H)-one derivatives as potential fXa inhibitors.

Xing J, Yang L, Yang Y, Zhao L, Wei Q, Zhang J, Zhou J, Zhang H. Xing J, et al. Eur J Med Chem. 2017 Jan 5;125:411-422. doi: 10.1016/j.ejmech.2016.09.055. Epub 2016 Sep 19. Eur J Med Chem. 2017. PMID: 27689724

8

Design, synthesis and biological evaluation of anthranilamide derivatives as potential factor Xa (fXa) inhibitors.

Xing J, Yang L, Zhou J, Zhang H. Xing J, et al. Bioorg Med Chem. 2018 Dec 15;26(23-24):5987-5999. doi: 10.1016/j.bmc.2018.09.012. Epub 2018 Sep 11. Bioorg Med Chem. 2018. PMID: 30446438

9

Rapid generation of novel benzoic acid-based xanthine derivatives as highly potent, selective and long acting DPP-4 inhibitors: Scaffold-hopping and prodrug study.

Li Q, Meng L, Zhou S, Deng X, Wang N, Ji Y, Peng Y, Xing J, Yao G. Li Q, et al. Among authors: xing j. Eur J Med Chem. 2019 Oct 15;180:509-523. doi: 10.1016/j.ejmech.2019.07.045. Epub 2019 Jul 16. Eur J Med Chem. 2019. PMID: 31336309

10

Optimization of the benzamide fragment targeting the S₂' site leads to potent dipeptidyl peptidase-IV inhibitors.

Deng X, Wang N, Meng L, Zhou S, Huang J, Xing J, He L, Jiang W, Li Q. Deng X, et al. Among authors: xing j. Bioorg Chem. 2020 Jan;94:103366. doi: 10.1016/j.bioorg.2019.103366. Epub 2019 Oct 15. Bioorg Chem. 2020. PMID: 31640932

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