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An engineered E. coli Nissle improves hyperammonemia and survival in mice and shows dose-dependent exposure in healthy humans.
Kurtz CB, Millet YA, Puurunen MK, Perreault M, Charbonneau MR, Isabella VM, Kotula JW, Antipov E, Dagon Y, Denney WS, Wagner DA, West KA, Degar AJ, Brennan AM, Miller PF. Kurtz CB, et al. Among authors: miller pf. Sci Transl Med. 2019 Jan 16;11(475):eaau7975. doi: 10.1126/scitranslmed.aau7975. Sci Transl Med. 2019. PMID: 30651324 Clinical Trial.
Immunotherapy with engineered bacteria by targeting the STING pathway for anti-tumor immunity.
Leventhal DS, Sokolovska A, Li N, Plescia C, Kolodziej SA, Gallant CW, Christmas R, Gao JR, James MJ, Abin-Fuentes A, Momin M, Bergeron C, Fisher A, Miller PF, West KA, Lora JM. Leventhal DS, et al. Among authors: miller pf. Nat Commun. 2020 Jun 1;11(1):2739. doi: 10.1038/s41467-020-16602-0. Nat Commun. 2020. PMID: 32483165 Free PMC article.
Engineering living therapeutics with synthetic biology.
Cubillos-Ruiz A, Guo T, Sokolovska A, Miller PF, Collins JJ, Lu TK, Lora JM. Cubillos-Ruiz A, et al. Among authors: miller pf. Nat Rev Drug Discov. 2021 Dec;20(12):941-960. doi: 10.1038/s41573-021-00285-3. Epub 2021 Oct 6. Nat Rev Drug Discov. 2021. PMID: 34616030 Review.
High Rates of Echocardiographic Abnormalities in an Underserved Population.
King SJ, Williamson C, Wheaten SA, Lobo JJ, Miller PF, Weickert TP, Hinderliter AL, Stouffer GA. King SJ, et al. Among authors: miller pf. JACC Adv. 2023 Sep 8;2(8):100618. doi: 10.1016/j.jacadv.2023.100618. eCollection 2023 Oct. JACC Adv. 2023. PMID: 38938357 Free PMC article. No abstract available.
57 results