van Dijk WJ - Search Results

1

Kinetic analysis of multistep USP7 mechanism shows critical role for target protein in activity.

Kim RQ, Geurink PP, Mulder MPC, Fish A, Ekkebus R, El Oualid F, van Dijk WJ, van Dalen D, Ovaa H, van Ingen H, Sixma TK. Kim RQ, et al. Among authors: van dijk wj. Nat Commun. 2019 Jan 16;10(1):231. doi: 10.1038/s41467-018-08231-5. Nat Commun. 2019. PMID: 30651545 Free PMC article.

2

The nucleosome acidic patch plays a critical role in RNF168-dependent ubiquitination of histone H2A.

Mattiroli F, Uckelmann M, Sahtoe DD, van Dijk WJ, Sixma TK. Mattiroli F, et al. Among authors: van dijk wj. Nat Commun. 2014;5:3291. doi: 10.1038/ncomms4291. Nat Commun. 2014. PMID: 24518117 Free PMC article.

3

Mechanism of UCH-L5 activation and inhibition by DEUBAD domains in RPN13 and INO80G.

Sahtoe DD, van Dijk WJ, El Oualid F, Ekkebus R, Ovaa H, Sixma TK. Sahtoe DD, et al. Among authors: van dijk wj. Mol Cell. 2015 Mar 5;57(5):887-900. doi: 10.1016/j.molcel.2014.12.039. Epub 2015 Feb 19. Mol Cell. 2015. PMID: 25702870 Free PMC article.

4

BAP1/ASXL1 recruitment and activation for H2A deubiquitination.

Sahtoe DD, van Dijk WJ, Ekkebus R, Ovaa H, Sixma TK. Sahtoe DD, et al. Among authors: van dijk wj. Nat Commun. 2016 Jan 7;7:10292. doi: 10.1038/ncomms10292. Nat Commun. 2016. PMID: 26739236 Free PMC article.

5

Structure of USP7 catalytic domain and three Ubl-domains reveals a connector α-helix with regulatory role.

Kim RQ, van Dijk WJ, Sixma TK. Kim RQ, et al. Among authors: van dijk wj. J Struct Biol. 2016 Jul;195(1):11-8. doi: 10.1016/j.jsb.2016.05.005. Epub 2016 May 13. J Struct Biol. 2016. PMID: 27183903 Free article.

6

Ubiquitin-specific protease 4 is inhibited by its ubiquitin-like domain.

Luna-Vargas MP, Faesen AC, van Dijk WJ, Rape M, Fish A, Sixma TK. Luna-Vargas MP, et al. Among authors: van dijk wj. EMBO Rep. 2011 Apr;12(4):365-72. doi: 10.1038/embor.2011.33. Epub 2011 Mar 18. EMBO Rep. 2011. Retraction in: EMBO Rep. 2014 Jan;15(1):121. doi: 10.1002/embr.201470010 PMID: 21415856 Free PMC article. Retracted.

7

The differential modulation of USP activity by internal regulatory domains, interactors and eight ubiquitin chain types.

Faesen AC, Luna-Vargas MP, Geurink PP, Clerici M, Merkx R, van Dijk WJ, Hameed DS, El Oualid F, Ovaa H, Sixma TK. Faesen AC, et al. Among authors: van dijk wj. Chem Biol. 2011 Dec 23;18(12):1550-61. doi: 10.1016/j.chembiol.2011.10.017. Chem Biol. 2011. PMID: 22195557

8

Target specificity of the E3 ligase LUBAC for ubiquitin and NEMO relies on different minimal requirements.

Smit JJ, van Dijk WJ, El Atmioui D, Merkx R, Ovaa H, Sixma TK. Smit JJ, et al. Among authors: van dijk wj. J Biol Chem. 2013 Nov 1;288(44):31728-37. doi: 10.1074/jbc.M113.495846. Epub 2013 Sep 12. J Biol Chem. 2013. PMID: 24030825 Free PMC article.

9

A conserved two-step binding for the UAF1 regulator to the USP12 deubiquitinating enzyme.

Dharadhar S, Clerici M, van Dijk WJ, Fish A, Sixma TK. Dharadhar S, et al. Among authors: van dijk wj. J Struct Biol. 2016 Dec;196(3):437-447. doi: 10.1016/j.jsb.2016.09.011. Epub 2016 Sep 17. J Struct Biol. 2016. PMID: 27650958 Free PMC article.

10

Insert L1 is a central hub for allosteric regulation of USP1 activity.

Dharadhar S, van Dijk WJ, Scheffers S, Fish A, Sixma TK. Dharadhar S, et al. Among authors: van dijk wj. EMBO Rep. 2021 Apr 7;22(4):e51749. doi: 10.15252/embr.202051749. Epub 2021 Feb 23. EMBO Rep. 2021. PMID: 33619839 Free PMC article.

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