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214 results

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American Association for Cancer Research Project Genomics Evidence Neoplasia Information Exchange: From Inception to First Data Release and Beyond-Lessons Learned and Member Institutions' Perspectives.
Micheel CM, Sweeney SM, LeNoue-Newton ML, André F, Bedard PL, Guinney J, Meijer GA, Rollins BJ, Sawyers CL, Schultz N, Shaw KRM, Velculescu VE, Levy MA; AACR Project GENIE Consortium. Micheel CM, et al. Among authors: velculescu ve. JCO Clin Cancer Inform. 2018 Dec;2:1-14. doi: 10.1200/CCI.17.00083. JCO Clin Cancer Inform. 2018. PMID: 30652542 Free PMC article. Review.
Diagnostic Strategies toward Clinical Implementation of Liquid Biopsy RAS/BRAF Circulating Tumor DNA Analyses in Patients with Metastatic Colorectal Cancer.
van 't Erve I, Greuter MJE, Bolhuis K, Vessies DCL, Leal A, Vink GR, van den Broek D, Velculescu VE, Punt CJA, Meijer GA, Coupé VMH, Fijneman RJA. van 't Erve I, et al. Among authors: velculescu ve. J Mol Diagn. 2020 Dec;22(12):1430-1437. doi: 10.1016/j.jmoldx.2020.09.002. Epub 2020 Sep 19. J Mol Diagn. 2020. PMID: 32961317 Free article.
Correlation Between Surrogate End Points and Overall Survival in a Multi-institutional Clinicogenomic Cohort of Patients With Non-Small Cell Lung or Colorectal Cancer.
Kehl KL, Riely GJ, Lepisto EM, Lavery JA, Warner JL, LeNoue-Newton ML, Sweeney SM, Rudolph JE, Brown S, Yu C, Bedard PL, Schrag D, Panageas KS; American Association of Cancer Research (AACR) Project Genomics Evidence Neoplasia Information Exchange (GENIE) Consortium. Kehl KL, et al. JAMA Netw Open. 2021 Jul 1;4(7):e2117547. doi: 10.1001/jamanetworkopen.2021.17547. JAMA Netw Open. 2021. PMID: 34309669 Free PMC article.
Implications of Selection Bias Due to Delayed Study Entry in Clinical Genomic Studies.
Brown S, Lavery JA, Shen R, Martin AS, Kehl KL, Sweeney SM, Lepisto EM, Rizvi H, McCarthy CG, Schultz N, Warner JL, Park BH, Bedard PL, Riely GJ, Schrag D, Panageas KS; AACR Project GENIE Consortium. Brown S, et al. JAMA Oncol. 2022 Feb 1;8(2):287-291. doi: 10.1001/jamaoncol.2021.5153. JAMA Oncol. 2022. PMID: 34734967 Free PMC article.
KRAS A146 Mutations Are Associated With Distinct Clinical Behavior in Patients With Colorectal Liver Metastases.
van 't Erve I, Wesdorp NJ, Medina JE, Ferreira L, Leal A, Huiskens J, Bolhuis K, van Waesberghe JTM, Swijnenburg RJ, van den Broek D, Velculescu VE, Kazemier G, Punt CJA, Meijer GA, Fijneman RJA. van 't Erve I, et al. Among authors: velculescu ve. JCO Precis Oncol. 2021 Nov 17;5:PO.21.00223. doi: 10.1200/PO.21.00223. eCollection 2021. JCO Precis Oncol. 2021. PMID: 34820593 Free PMC article.
Metastatic Colorectal Cancer Treatment Response Evaluation by Ultra-Deep Sequencing of Cell-Free DNA and Matched White Blood Cells.
van 't Erve I, Medina JE, Leal A, Papp E, Phallen J, Adleff V, Chiao EJ, Arun AS, Bolhuis K, Simmons JK, Karandikar A, Valkenburg KC, Sausen M, Angiuoli SV, Scharpf RB, Punt CJA, Meijer GA, Velculescu VE, Fijneman RJA. van 't Erve I, et al. Among authors: velculescu ve. Clin Cancer Res. 2023 Mar 1;29(5):899-909. doi: 10.1158/1078-0432.CCR-22-2538. Clin Cancer Res. 2023. PMID: 36534496 Free PMC article. Clinical Trial.
Cell-free DNA approaches for cancer early detection and interception.
Medina JE, Dracopoli NC, Bach PB, Lau A, Scharpf RB, Meijer GA, Andersen CL, Velculescu VE. Medina JE, et al. Among authors: velculescu ve. J Immunother Cancer. 2023 Sep;11(9):e006013. doi: 10.1136/jitc-2022-006013. J Immunother Cancer. 2023. PMID: 37696619 Free PMC article. Review.
Early Detection of Ovarian Cancer Using Cell-Free DNA Fragmentomes and Protein Biomarkers.
Medina JE, Annapragada AV, Lof P, Short S, Bartolomucci AL, Mathios D, Koul S, Niknafs N, Noë M, Foda ZH, Bruhm DC, Hruban C, Vulpescu NA, Jung E, Dua R, Canzoniero JV, Cristiano S, Adleff V, Symecko H, van den Broek D, Sokoll LJ, Baylin SB, Press MF, Slamon DJ, Konecny GE, Therkildsen C, Carvalho B, Meijer GA, Andersen CL, Domchek SM, Drapkin R, Scharpf RB, Phallen J, Lok CAR, Velculescu VE. Medina JE, et al. Among authors: velculescu ve. Cancer Discov. 2025 Jan 13;15(1):105-118. doi: 10.1158/2159-8290.CD-24-0393. Cancer Discov. 2025. PMID: 39345137 Free PMC article.
Cancer treatment monitoring using cell-free DNA fragmentomes.
van 't Erve I, Alipanahi B, Lumbard K, Skidmore ZL, Rinaldi L, Millberg LK, Carey J, Chesnick B, Cristiano S, Portwood C, Wu T, Peters E, Bolhuis K, Punt CJA, Tom J, Bach PB, Dracopoli NC, Meijer GA, Scharpf RB, Velculescu VE, Fijneman RJA, Leal A. van 't Erve I, et al. Among authors: velculescu ve. Nat Commun. 2024 Oct 21;15(1):8801. doi: 10.1038/s41467-024-53017-7. Nat Commun. 2024. PMID: 39433569 Free PMC article.
214 results