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Organic cation transporter 3 (Oct3) is a distinct catecholamines clearance route in adipocytes mediating the beiging of white adipose tissue.
Song W, Luo Q, Zhang Y, Zhou L, Liu Y, Ma Z, Guo J, Huang Y, Cheng L, Meng Z, Li Z, Zhang B, Li S, Yee SW, Fan H, Li P, Giacomini KM, Chen L. Song W, et al. Among authors: ma z. PLoS Biol. 2019 Jan 17;17(1):e2006571. doi: 10.1371/journal.pbio.2006571. eCollection 2019 Jan. PLoS Biol. 2019. PMID: 30653498 Free PMC article.
Zoledronate dysregulates fatty acid metabolism in renal tubular epithelial cells to induce nephrotoxicity.
Cheng L, Ge M, Lan Z, Ma Z, Chi W, Kuang W, Sun K, Zhao X, Liu Y, Feng Y, Huang Y, Luo M, Li L, Zhang B, Hu X, Xu L, Liu X, Huo Y, Deng H, Yang J, Xi Q, Zhang Y, Siegenthaler JA, Chen L. Cheng L, et al. Among authors: ma z. Arch Toxicol. 2018 Jan;92(1):469-485. doi: 10.1007/s00204-017-2048-0. Epub 2017 Sep 4. Arch Toxicol. 2018. PMID: 28871336 Free PMC article.
Cholesterol biosynthesis supports the growth of hepatocarcinoma lesions depleted of fatty acid synthase in mice and humans.
Che L, Chi W, Qiao Y, Zhang J, Song X, Liu Y, Li L, Jia J, Pilo MG, Wang J, Cigliano A, Ma Z, Kuang W, Tang Z, Zhang Z, Shui G, Ribback S, Dombrowski F, Evert M, Pascale RM, Cossu C, Pes GM, Osborne TF, Calvisi DF, Chen X, Chen L. Che L, et al. Among authors: ma z. Gut. 2020 Jan;69(1):177-186. doi: 10.1136/gutjnl-2018-317581. Epub 2019 Apr 6. Gut. 2020. PMID: 30954949 Free PMC article.
A highly selective PI3Kδ inhibitor BGB-10188 shows superior preclinical anti-tumor activities and decreased on-target side effects on colon.
Yang X, Bai H, Yuan X, Yang X, Liu Y, Guo M, Hu N, Jiang B, Lian Z, Ma Z, Wang J, Sun X, Zhang T, Su D, Wu Y, Li J, Wang F, Wang Z, Wang L, Liu X, Song X. Yang X, et al. Among authors: ma z. Neoplasia. 2024 Nov;57:101053. doi: 10.1016/j.neo.2024.101053. Epub 2024 Sep 10. Neoplasia. 2024. PMID: 39260132 Free PMC article.
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