Nys M - Search Results

1

Structure-Guided Exploration of SDS22 Interactions with Protein Phosphatase PP1 and the Splicing Factor BCLAF1.

Heroes E, Van der Hoeven G, Choy MS, Garcia JDP, Ferreira M, Nys M, Derua R, Beullens M, Ulens C, Peti W, Van Meervelt L, Page R, Bollen M. Heroes E, et al. Among authors: nys m. Structure. 2019 Mar 5;27(3):507-518.e5. doi: 10.1016/j.str.2018.12.002. Epub 2019 Jan 17. Structure. 2019. PMID: 30661852 Free PMC article.

2

Structural insights into Cys-loop receptor function and ligand recognition.

Nys M, Kesters D, Ulens C. Nys M, et al. Biochem Pharmacol. 2013 Oct 15;86(8):1042-53. doi: 10.1016/j.bcp.2013.07.001. Epub 2013 Jul 10. Biochem Pharmacol. 2013. PMID: 23850718 Review.

3

Structure of the SthK carboxy-terminal region reveals a gating mechanism for cyclic nucleotide-modulated ion channels.

Kesters D, Brams M, Nys M, Wijckmans E, Spurny R, Voets T, Tytgat J, Kusch J, Ulens C. Kesters D, et al. Among authors: nys m. PLoS One. 2015 Jan 27;10(1):e0116369. doi: 10.1371/journal.pone.0116369. eCollection 2015. PLoS One. 2015. PMID: 25625648 Free PMC article.

4

Functional and Biochemical Characterization of Alvinella pompejana Cys-Loop Receptor Homologues.

Wijckmans E, Nys M, Debaveye S, Brams M, Pardon E, Willegems K, Bertrand D, Steyaert J, Efremov R, Ulens C. Wijckmans E, et al. Among authors: nys m. PLoS One. 2016 Mar 21;11(3):e0151183. doi: 10.1371/journal.pone.0151183. eCollection 2016. PLoS One. 2016. PMID: 26999666 Free PMC article.

5

Allosteric binding site in a Cys-loop receptor ligand-binding domain unveiled in the crystal structure of ELIC in complex with chlorpromazine.

Nys M, Wijckmans E, Farinha A, Yoluk Ö, Andersson M, Brams M, Spurny R, Peigneur S, Tytgat J, Lindahl E, Ulens C. Nys M, et al. Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):E6696-E6703. doi: 10.1073/pnas.1603101113. Epub 2016 Oct 10. Proc Natl Acad Sci U S A. 2016. PMID: 27791038 Free PMC article.

6

The structural basis for an on-off switch controlling Gβγ-mediated inhibition of TRPM3 channels.

Behrendt M, Gruss F, Enzeroth R, Dembla S, Zhao S, Crassous PA, Mohr F, Nys M, Louros N, Gallardo R, Zorzini V, Wagner D, Economou A, Rousseau F, Schymkowitz J, Philipp SE, Rohacs T, Ulens C, Oberwinkler J. Behrendt M, et al. Among authors: nys m. Proc Natl Acad Sci U S A. 2020 Nov 17;117(46):29090-29100. doi: 10.1073/pnas.2001177117. Epub 2020 Oct 29. Proc Natl Acad Sci U S A. 2020. PMID: 33122432 Free PMC article.

7

The molecular mechanism of snake short-chain α-neurotoxin binding to muscle-type nicotinic acetylcholine receptors.

Nys M, Zarkadas E, Brams M, Mehregan A, Kambara K, Kool J, Casewell NR, Bertrand D, Baenziger JE, Nury H, Ulens C. Nys M, et al. Nat Commun. 2022 Aug 4;13(1):4543. doi: 10.1038/s41467-022-32174-7. Nat Commun. 2022. PMID: 35927270 Free PMC article.

8

An in vitro assay to investigate venom neurotoxin activity on muscle-type nicotinic acetylcholine receptor activation and for the discovery of toxin-inhibitory molecules.

Patel RN, Clare RH, Ledsgaard L, Nys M, Kool J, Laustsen AH, Ulens C, Casewell NR. Patel RN, et al. Among authors: nys m. Biochem Pharmacol. 2023 Oct;216:115758. doi: 10.1016/j.bcp.2023.115758. Epub 2023 Aug 20. Biochem Pharmacol. 2023. PMID: 37604290 Free PMC article.

9

Author Correction: The molecular mechanism of snake short-chain α-neurotoxin binding to muscle-type nicotinic acetylcholine receptors.

Nys M, Zarkadas E, Brams M, Mehregan A, Kambara K, Kool J, Casewell NR, Bertrand D, Baenziger JE, Nury H, Ulens C. Nys M, et al. Nat Commun. 2024 May 28;15(1):4532. doi: 10.1038/s41467-024-48904-y. Nat Commun. 2024. PMID: 38806512 Free PMC article. No abstract available.

10

Insights into the structural determinants required for high-affinity binding of chiral cyclopropane-containing ligands to α4β2-nicotinic acetylcholine receptors: an integrated approach to behaviorally active nicotinic ligands.

Zhang HK, Eaton JB, Yu LF, Nys M, Mazzolari A, van Elk R, Smit AB, Alexandrov V, Hanania T, Sabath E, Fedolak A, Brunner D, Lukas RJ, Vistoli G, Ulens C, Kozikowski AP. Zhang HK, et al. Among authors: nys m. J Med Chem. 2012 Sep 27;55(18):8028-37. doi: 10.1021/jm3008739. Epub 2012 Sep 7. J Med Chem. 2012. PMID: 22928944 Free PMC article.

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