Ablation of the microRNA-17-92 cluster in neural stem cells diminishes adult hippocampal neurogenesis and cognitive function.
Pan WL, Chopp M, Fan B, Zhang R, Wang X, Hu J, Zhang XM, Zhang ZG, Liu XS.
Pan WL, et al. Among authors: zhang xm, zhang r, zhang zg.
FASEB J. 2019 Apr;33(4):5257-5267. doi: 10.1096/fj.201801019R. Epub 2019 Jan 22.
FASEB J. 2019.
PMID: 30668139
Free PMC article.
Our study demonstrates that the miR-17-92 cluster in NSCs is critical for cognitive and behavioral function and regulates neurogenesis and that the miR-17-92 cluster may target ENH1/ID1 signaling.-Pan, W. L., Chopp, M., Fan, B., Zhang, R., Wang, X., Hu, J., Zhang …
Our study demonstrates that the miR-17-92 cluster in NSCs is critical for cognitive and behavioral function and regulates neurogenesis and t …