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Use of a bacteriophage lysin to identify a novel target for antimicrobial development.
Schuch R, Pelzek AJ, Raz A, Euler CW, Ryan PA, Winer BY, Farnsworth A, Bhaskaran SS, Stebbins CE, Xu Y, Clifford A, Bearss DJ, Vankayalapati H, Goldberg AR, Fischetti VA. Schuch R, et al. PLoS One. 2013 Apr 10;8(4):e60754. doi: 10.1371/journal.pone.0060754. Print 2013. PLoS One. 2013. PMID: 23593301 Free PMC article.
Lysins: the arrival of pathogen-directed anti-infectives.
Pastagia M, Schuch R, Fischetti VA, Huang DB. Pastagia M, et al. Among authors: schuch r. J Med Microbiol. 2013 Oct;62(Pt 10):1506-1516. doi: 10.1099/jmm.0.061028-0. Epub 2013 Jun 27. J Med Microbiol. 2013. PMID: 23813275 Review.
Combination therapy with lysin CF-301 and antibiotic is superior to antibiotic alone for treating methicillin-resistant Staphylococcus aureus-induced murine bacteremia.
Schuch R, Lee HM, Schneider BC, Sauve KL, Law C, Khan BK, Rotolo JA, Horiuchi Y, Couto DE, Raz A, Fischetti VA, Huang DB, Nowinski RC, Wittekind M. Schuch R, et al. J Infect Dis. 2014 May 1;209(9):1469-78. doi: 10.1093/infdis/jit637. Epub 2013 Nov 28. J Infect Dis. 2014. PMID: 24286983 Free PMC article.
146 results