Nakamura Y - Search Results

1

Maternal Embryonic Leucine Zipper Kinase (MELK), a Potential Therapeutic Target for Neuroblastoma.

Chlenski A, Park C, Dobratic M, Salwen HR, Budke B, Park JH, Miller R, Applebaum MA, Wilkinson E, Nakamura Y, Connell PP, Cohn SL. Chlenski A, et al. Among authors: nakamura y. Mol Cancer Ther. 2019 Mar;18(3):507-516. doi: 10.1158/1535-7163.MCT-18-0819. Epub 2019 Jan 23. Mol Cancer Ther. 2019. PMID: 30674566 Free PMC article.

2

Effective growth-suppressive activity of maternal embryonic leucine-zipper kinase (MELK) inhibitor against small cell lung cancer.

Inoue H, Kato T, Olugbile S, Tamura K, Chung S, Miyamoto T, Matsuo Y, Salgia R, Nakamura Y, Park JH. Inoue H, et al. Among authors: nakamura y. Oncotarget. 2016 Mar 22;7(12):13621-33. doi: 10.18632/oncotarget.7297. Oncotarget. 2016. PMID: 26871945 Free PMC article.

3

MELK inhibition targets cancer stem cells through downregulation of SOX2 expression in head and neck cancer cells.

Ren L, Deng B, Saloura V, Park JH, Nakamura Y. Ren L, et al. Among authors: nakamura y. Oncol Rep. 2019 Apr;41(4):2540-2548. doi: 10.3892/or.2019.6988. Epub 2019 Jan 30. Oncol Rep. 2019. PMID: 30720113

4

Involvement of maternal embryonic leucine zipper kinase (MELK) in mammary carcinogenesis through interaction with Bcl-G, a pro-apoptotic member of the Bcl-2 family.

Lin ML, Park JH, Nishidate T, Nakamura Y, Katagiri T. Lin ML, et al. Among authors: nakamura y. Breast Cancer Res. 2007;9(1):R17. doi: 10.1186/bcr1650. Breast Cancer Res. 2007. PMID: 17280616 Free PMC article.

5

Oncogenic roles of TOPK and MELK, and effective growth suppression by small molecular inhibitors in kidney cancer cells.

Kato T, Inoue H, Imoto S, Tamada Y, Miyamoto T, Matsuo Y, Nakamura Y, Park JH. Kato T, et al. Among authors: nakamura y. Oncotarget. 2016 Apr 5;7(14):17652-64. doi: 10.18632/oncotarget.7755. Oncotarget. 2016. PMID: 26933922 Free PMC article.

6

T-LAK Cell-Originated Protein Kinase (TOPK) as a Prognostic Factor and a Potential Therapeutic Target in Ovarian Cancer.

Ikeda Y, Park JH, Miyamoto T, Takamatsu N, Kato T, Iwasa A, Okabe S, Imai Y, Fujiwara K, Nakamura Y, Hasegawa K. Ikeda Y, et al. Among authors: nakamura y. Clin Cancer Res. 2016 Dec 15;22(24):6110-6117. doi: 10.1158/1078-0432.CCR-16-0207. Epub 2016 Jun 22. Clin Cancer Res. 2016. PMID: 27334838

7

TOPK (T-LAK cell-originated protein kinase) inhibitor exhibits growth suppressive effect on small cell lung cancer.

Park JH, Inoue H, Kato T, Zewde M, Miyamoto T, Matsuo Y, Salgia R, Nakamura Y. Park JH, et al. Among authors: nakamura y. Cancer Sci. 2017 Mar;108(3):488-496. doi: 10.1111/cas.13160. Cancer Sci. 2017. PMID: 28075524 Free PMC article.

8

Effects of SMYD2-mediated EML4-ALK methylation on the signaling pathway and growth in non-small-cell lung cancer cells.

Wang R, Deng X, Yoshioka Y, Vougiouklakis T, Park JH, Suzuki T, Dohmae N, Ueda K, Hamamoto R, Nakamura Y. Wang R, et al. Among authors: nakamura y. Cancer Sci. 2017 Jun;108(6):1203-1209. doi: 10.1111/cas.13245. Cancer Sci. 2017. PMID: 28370702 Free PMC article.

9

Development of small molecular compounds targeting cancer stem cells.

Park JH, Chung S, Matsuo Y, Nakamura Y. Park JH, et al. Among authors: nakamura y. Medchemcomm. 2016 Nov 11;8(1):73-80. doi: 10.1039/c6md00385k. eCollection 2017 Jan 1. Medchemcomm. 2016. PMID: 30108692 Free PMC article. Review.

10

Potent anti-myeloma activity of the TOPK inhibitor OTS514 in pre-clinical models.

Stefka AT, Johnson D, Rosebeck S, Park JH, Nakamura Y, Jakubowiak AJ. Stefka AT, et al. Among authors: nakamura y. Cancer Med. 2020 Jan;9(1):324-334. doi: 10.1002/cam4.2695. Epub 2019 Nov 12. Cancer Med. 2020. PMID: 31714026 Free PMC article.

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