Ye J - Search Results

1

Discovery of a potent tyrosine kinase AXL inhibitor bearing the 3-((2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)amino)pyrazine core.

Wang Y, Xing L, Ji Y, Ye J, Dai Y, Gu W, Ai J, Song Z. Wang Y, et al. Among authors: ye j. Bioorg Med Chem Lett. 2019 Mar 15;29(6):836-838. doi: 10.1016/j.bmcl.2019.01.018. Epub 2019 Jan 21. Bioorg Med Chem Lett. 2019. PMID: 30685094

2

Design and discovery of 4-anilinoquinazoline-urea derivatives as dual TK inhibitors of EGFR and VEGFR-2.

Zhang HQ, Gong FH, Ye JQ, Zhang C, Yue XH, Li CG, Xu YG, Sun LP. Zhang HQ, et al. Eur J Med Chem. 2017 Jan 5;125:245-254. doi: 10.1016/j.ejmech.2016.09.039. Epub 2016 Sep 14. Eur J Med Chem. 2017. PMID: 27688180

3

Novel N-Substituted oseltamivir derivatives as potent influenza neuraminidase inhibitors: Design, synthesis, biological evaluation, ADME prediction and molecular docking studies.

Ye J, Yang X, Xu M, Chan PK, Ma C. Ye J, et al. Eur J Med Chem. 2019 Nov 15;182:111635. doi: 10.1016/j.ejmech.2019.111635. Epub 2019 Aug 22. Eur J Med Chem. 2019. PMID: 31493744

4

Discovery of Antibacterials That Inhibit Bacterial RNA Polymerase Interactions with Sigma Factors.

Ye J, Chu AJ, Harper R, Chan ST, Shek TL, Zhang Y, Ip M, Sambir M, Artsimovitch I, Zuo Z, Yang X, Ma C. Ye J, et al. J Med Chem. 2020 Jul 23;63(14):7695-7720. doi: 10.1021/acs.jmedchem.0c00520. Epub 2020 Jul 7. J Med Chem. 2020. PMID: 32633513 Free PMC article.

5

Sulfonamidyl derivatives of sigmacidin: Protein-protein interaction inhibitors targeting bacterial RNA polymerase and sigma factor interaction exhibiting antimicrobial activity against antibiotic-resistant bacteria.

Ye J, Kan CH, Zheng Y, Tsang TF, Chu AJ, Chan KH, Yang X, Ma C. Ye J, et al. Bioorg Chem. 2024 Feb;143:106983. doi: 10.1016/j.bioorg.2023.106983. Epub 2023 Nov 23. Bioorg Chem. 2024. PMID: 38016396

6

Benzyl and benzoyl benzoic acid inhibitors of bacterial RNA polymerase-sigma factor interaction.

Ye J, Chu AJ, Lin L, Chan ST, Harper R, Xiao M, Artsimovitch I, Zuo Z, Ma C, Yang X. Ye J, et al. Eur J Med Chem. 2020 Dec 15;208:112671. doi: 10.1016/j.ejmech.2020.112671. Epub 2020 Aug 18. Eur J Med Chem. 2020. PMID: 32920341 Free PMC article.

7

Anti-inflammatory effect of the six compounds isolated from Nauclea officinalis Pierrc ex Pitard, and molecular mechanism of strictosamide via suppressing the NF-κB and MAPK signaling pathway in LPS-induced RAW 264.7 macrophages.

Li D, Chen J, Ye J, Zhai X, Song J, Jiang C, Wang J, Zhang H, Jia X, Zhu F. Li D, et al. Among authors: ye j. J Ethnopharmacol. 2017 Jan 20;196:66-74. doi: 10.1016/j.jep.2016.12.007. Epub 2016 Dec 15. J Ethnopharmacol. 2017. PMID: 27989509

8

Inhibition of bacterial RNA polymerase function and protein-protein interactions: a promising approach for next-generation antibacterial therapeutics.

Ye J, Kan CH, Yang X, Ma C. Ye J, et al. RSC Med Chem. 2024 Mar 26;15(5):1471-1487. doi: 10.1039/d3md00690e. eCollection 2024 May 22. RSC Med Chem. 2024. PMID: 38784472 Review.

9

First-In-Class Inhibitors Targeting the Interaction between Bacterial RNA Polymerase and Sigma Initiation Factor Affect the Viability and Toxin Release of Streptococcus pneumoniae.

Ye J, Chu AJ, Lin L, Yang X, Ma C. Ye J, et al. Molecules. 2019 Aug 9;24(16):2902. doi: 10.3390/molecules24162902. Molecules. 2019. PMID: 31405060 Free PMC article.

10

Nauclea officinalis inhibits inflammation in LPS-mediated RAW 264.7 macrophages by suppressing the NF-κB signaling pathway.

Zhai XT, Zhang ZY, Jiang CH, Chen JQ, Ye JQ, Jia XB, Yang Y, Ni Q, Wang SX, Song J, Zhu FX. Zhai XT, et al. Among authors: ye jq. J Ethnopharmacol. 2016 May 13;183:159-165. doi: 10.1016/j.jep.2016.01.018. Epub 2016 Jan 19. J Ethnopharmacol. 2016. PMID: 26806575

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