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The affinity of newly synthesized proteoglycan for hyaluronic acid can be enhanced by exposure to mild alkali.
Plaas AH, Sandy JD. Plaas AH, et al. Biochem J. 1986 Feb 15;234(1):221-3. doi: 10.1042/bj2340221. Biochem J. 1986. PMID: 3707543 Free PMC article.
In mixtures prepared at pH 6.8 the newly synthesized proteoglycan had the lower affinity; however, in mixtures incubated at pH 8.5 for 24 h before addition of hyaluronic acid, the newly synthesized proteoglycan exhibited a markedly higher affinity than the bovine monomer. …
In mixtures prepared at pH 6.8 the newly synthesized proteoglycan had the lower affinity; however, in mixtures incubated at pH 8.5 for 24 h …
A sensitive assay for active link protein from cartilage.
Sandy JD, Plaas AH. Sandy JD, et al. Among authors: plaas ah. Biochem J. 1985 Dec 1;232(2):613-6. doi: 10.1042/bj2320613. Biochem J. 1985. PMID: 4091812 Free PMC article.
A new assay for the activity of cartilage link protein is described. The method is based on the finding [Plaas, Sandy & Muir (1983) Biochem. ...
A new assay for the activity of cartilage link protein is described. The method is based on the finding [Plaas, Sandy & Mu
Superficial zone chondrocytes in normal and osteoarthritic human articular cartilages synthesize novel truncated forms of inter-alpha-trypsin inhibitor heavy chains which are attached to a chondroitin sulfate proteoglycan other than bikunin.
Yoshihara Y, Plaas A, Osborn B, Margulis A, Nelson F, Stewart M, Rugg MS, Milner CM, Day AJ, Nemoto K, Sandy JD. Yoshihara Y, et al. Among authors: plaas a. Osteoarthritis Cartilage. 2008 Nov;16(11):1343-55. doi: 10.1016/j.joca.2008.04.004. Epub 2008 Jun 3. Osteoarthritis Cartilage. 2008. PMID: 18524635 Free article.
105 results