Liang G - Search Results

1

Critical Role of SREBP-1c Large-VLDL Pathway in Environment-Induced Hypertriglyceridemia of Apo AV Deficiency.

Takanashi M, Kimura T, Li C, Tanaka M, Matsuhashi A, Yoshida H, Noda A, Xu P, Takase S, Okazaki S, Iizuka Y, Kumagai H, Ikeda Y, Gotoda T, Takahashi M, Yagyu H, Ishibashi S, Yamauchi T, Kadowaki T, Liang G, Okazaki H. Takanashi M, et al. Among authors: liang g. Arterioscler Thromb Vasc Biol. 2019 Mar;39(3):373-386. doi: 10.1161/ATVBAHA.118.311931. Arterioscler Thromb Vasc Biol. 2019. PMID: 30700132 Free PMC article.

2

Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c.

Liang G, Yang J, Horton JD, Hammer RE, Goldstein JL, Brown MS. Liang G, et al. J Biol Chem. 2002 Mar 15;277(11):9520-8. doi: 10.1074/jbc.M111421200. Epub 2002 Jan 8. J Biol Chem. 2002. PMID: 11782483 Free article.

3

Overexpression of Insig-1 in the livers of transgenic mice inhibits SREBP processing and reduces insulin-stimulated lipogenesis.

Engelking LJ, Kuriyama H, Hammer RE, Horton JD, Brown MS, Goldstein JL, Liang G. Engelking LJ, et al. Among authors: liang g. J Clin Invest. 2004 Apr;113(8):1168-75. doi: 10.1172/JCI20978. J Clin Invest. 2004. PMID: 15085196 Free PMC article.

4

Central role for liver X receptor in insulin-mediated activation of Srebp-1c transcription and stimulation of fatty acid synthesis in liver.

Chen G, Liang G, Ou J, Goldstein JL, Brown MS. Chen G, et al. Among authors: liang g. Proc Natl Acad Sci U S A. 2004 Aug 3;101(31):11245-50. doi: 10.1073/pnas.0404297101. Epub 2004 Jul 20. Proc Natl Acad Sci U S A. 2004. PMID: 15266058 Free PMC article.

5

Schoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteins.

Engelking LJ, Liang G, Hammer RE, Takaishi K, Kuriyama H, Evers BM, Li WP, Horton JD, Goldstein JL, Brown MS. Engelking LJ, et al. Among authors: liang g. J Clin Invest. 2005 Sep;115(9):2489-98. doi: 10.1172/JCI25614. Epub 2005 Aug 11. J Clin Invest. 2005. PMID: 16100574 Free PMC article.

6

LXR-SREBP-1c-phospholipid transfer protein axis controls very low density lipoprotein (VLDL) particle size.

Okazaki H, Goldstein JL, Brown MS, Liang G. Okazaki H, et al. Among authors: liang g. J Biol Chem. 2010 Feb 26;285(9):6801-10. doi: 10.1074/jbc.M109.079459. Epub 2009 Dec 27. J Biol Chem. 2010. PMID: 20037162 Free PMC article.

7

The Scap/SREBP pathway is essential for developing diabetic fatty liver and carbohydrate-induced hypertriglyceridemia in animals.

Moon YA, Liang G, Xie X, Frank-Kamenetsky M, Fitzgerald K, Koteliansky V, Brown MS, Goldstein JL, Horton JD. Moon YA, et al. Among authors: liang g. Cell Metab. 2012 Feb 8;15(2):240-6. doi: 10.1016/j.cmet.2011.12.017. Cell Metab. 2012. PMID: 22326225 Free PMC article.

8

Insulin stimulation of SREBP-1c processing in transgenic rat hepatocytes requires p70 S6-kinase.

Owen JL, Zhang Y, Bae SH, Farooqi MS, Liang G, Hammer RE, Goldstein JL, Brown MS. Owen JL, et al. Among authors: liang g. Proc Natl Acad Sci U S A. 2012 Oct 2;109(40):16184-9. doi: 10.1073/pnas.1213343109. Epub 2012 Aug 27. Proc Natl Acad Sci U S A. 2012. PMID: 22927400 Free PMC article.

9

Expression of SREBP-1c Requires SREBP-2-mediated Generation of a Sterol Ligand for LXR in Livers of Mice.

Rong S, Cortés VA, Rashid S, Anderson NN, McDonald JG, Liang G, Moon YA, Hammer RE, Horton JD. Rong S, et al. Among authors: liang g. Elife. 2017 Feb 28;6:e25015. doi: 10.7554/eLife.25015. Elife. 2017. PMID: 28244871 Free PMC article.

10

Developmental and extrahepatic physiological functions of SREBP pathway genes in mice.

Engelking LJ, Cantoria MJ, Xu Y, Liang G. Engelking LJ, et al. Among authors: liang g. Semin Cell Dev Biol. 2018 Sep;81:98-109. doi: 10.1016/j.semcdb.2017.07.011. Epub 2017 Jul 20. Semin Cell Dev Biol. 2018. PMID: 28736205 Free PMC article. Review.

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