Ikehara M - Search Results

1

Conversion of the guanine nucleotide binding sites of ras protein resulting in the reduction of base specificity.

Miura K, Kamiya H, Kubota S, Ikehara M, Nishimura S, Ohtsuka E. Miura K, et al. Among authors: ikehara m. Protein Eng. 1988 Sep;2(3):227-31. doi: 10.1093/protein/2.3.227. Protein Eng. 1988. PMID: 3070545

2

Expression of the amino terminal part of synthetic human growth hormone gene and somatomedin-like activity of expressed protein.

Doi T, Tokunaga T, Ohtsuka E, Hiraki Y, Suzuki F, Ikehara M. Doi T, et al. Among authors: ikehara m. Protein Eng. 1986 Oct-Nov;1(1):17-21. doi: 10.1093/protein/1.1.17. Protein Eng. 1986. PMID: 3333840

3

Hydrophobic effects on protein/nucleic acid interaction: enhancement of substrate binding by mutating tyrosine 45 to tryptophan in ribonuclease T1.

Hakoshima T, Tanaka M, Itoh T, Tomita KI, Amisaki T, Nishikawa S, Morioka H, Uesugi S, Ohtsuka E, Ikehara M. Hakoshima T, et al. Among authors: ikehara m. Protein Eng. 1991 Oct;4(7):793-9. doi: 10.1093/protein/4.7.793. Protein Eng. 1991. PMID: 1724696

4

27 amino acid residues can be deleted from the N-terminus of human lymphotoxin without impairment of its cytotoxic activity.

Nishikawa S, Matsuo N, Isaka Y, Uesugi S, Miura K, Ohtsuka E, Takeda K, Konno K, Ikehara M. Nishikawa S, et al. Among authors: ikehara m. J Mol Recognit. 1990 Apr;3(2):94-9. doi: 10.1002/jmr.300030207. J Mol Recognit. 1990. PMID: 2361063

5

Efficient cleavage by alpha-thrombin of a recombinant fused protein which contains insulin-like growth factor I.

Nishikawa S, Yanase K, Tokunaga-Doi T, Kodama K, Gomi H, Uesugi S, Ohtsuka E, Kato Y, Suzuki F, Ikehara M. Nishikawa S, et al. Among authors: ikehara m. Protein Eng. 1987 Dec;1(6):487-92. doi: 10.1093/protein/1.6.487. Protein Eng. 1987. PMID: 3334100

6

Non-cognizable ribonucleotide, 2'AMP, binds to a mutant ribonuclease T1 (Y45W) at a new base-binding site but not at the guanine-recognition site.

Hakoshima T, Itoh T, Gohda K, Tomita K, Uesugi S, Nishikawa S, Morioka H, Ohtsuka E, Ikehara M. Hakoshima T, et al. Among authors: ikehara m. FEBS Lett. 1991 Sep 23;290(1-2):216-20. doi: 10.1016/0014-5793(91)81263-8. FEBS Lett. 1991. PMID: 1655533 Free article.

7

Synthesis and expression of a synthetic gene for the activated human c-Ha-ras protein.

Miura K, Inoue Y, Nakamori H, Iwai S, Ohtsuka E, Ikehara M, Noguchi S, Nishimura S. Miura K, et al. Among authors: ikehara m. Jpn J Cancer Res. 1986 Jan;77(1):45-51. Jpn J Cancer Res. 1986. PMID: 3082814

8

Glu 46 of ribonuclease T1 is an essential residue for the recognition of guanine base.

Nishikawa S, Kimura T, Morioka H, Uesugi S, Hakoshima T, Tomita K, Ohtsuka E, Ikehara M. Nishikawa S, et al. Among authors: ikehara m. Biochem Biophys Res Commun. 1988 Jan 15;150(1):68-74. doi: 10.1016/0006-291x(88)90487-1. Biochem Biophys Res Commun. 1988. PMID: 3122758

9

Increase in nucleolytic activity of ribonuclease T1 by substitution of tryptophan 45 for tyrosine 45.

Nishikawa S, Morioka H, Kimura T, Ueda Y, Tanaka T, Uesugi S, Hakoshima T, Tomita K, Ohtsuka E, Ikehara M. Nishikawa S, et al. Among authors: ikehara m. Eur J Biochem. 1988 Apr 15;173(2):389-94. doi: 10.1111/j.1432-1033.1988.tb14011.x. Eur J Biochem. 1988. PMID: 3129293 Free article.

The gene for the mutant RNase T1 (Tyr45----Trp45), in which a single amino acid at the binding site of the guanine base has been changed, was constructed by the cassette mutangenesis method using a chemically synthesized gene [Ikehara, M. et al. (1986) Proc. Natl Ac …

The gene for the mutant RNase T1 (Tyr45----Trp45), in which a single amino acid at the binding site of the guanine base has been changed, wa …

10

Overproduction of cellular and activated Ha-ras proteins by mutating a synthetic gene.

Miura K, Kamiya H, Tominaga M, Inoue Y, Ikehara M, Noguchi S, Nishimura S, Ohtsuka E. Miura K, et al. Among authors: ikehara m. Chem Pharm Bull (Tokyo). 1987 Dec;35(12):4878-82. doi: 10.1248/cpb.35.4878. Chem Pharm Bull (Tokyo). 1987. PMID: 3330471 No abstract available.

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