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Transcription factor Stat3 stimulates metastatic behavior of human prostate cancer cells in vivo, whereas Stat5b has a preferential role in the promotion of prostate cancer cell viability and tumor growth.
Gu L, Dagvadorj A, Lutz J, Leiby B, Bonuccelli G, Lisanti MP, Addya S, Fortina P, Dasgupta A, Hyslop T, Bubendorf L, Nevalainen MT. Gu L, et al. Among authors: addya s. Am J Pathol. 2010 Apr;176(4):1959-72. doi: 10.2353/ajpath.2010.090653. Epub 2010 Feb 18. Am J Pathol. 2010. PMID: 20167868 Free PMC article.
The retinoblastoma tumor suppressor modulates DNA repair and radioresponsiveness.
Thangavel C, Boopathi E, Ciment S, Liu Y, O'Neill R, Sharma A, McMahon SB, Mellert H, Addya S, Ertel A, Birbe R, Fortina P, Dicker AP, Knudsen KE, Den RB. Thangavel C, et al. Among authors: addya s. Clin Cancer Res. 2014 Nov 1;20(21):5468-5482. doi: 10.1158/1078-0432.CCR-14-0326. Epub 2014 Aug 27. Clin Cancer Res. 2014. PMID: 25165096 Free PMC article.
RB Loss Promotes Prostate Cancer Metastasis.
Thangavel C, Boopathi E, Liu Y, Haber A, Ertel A, Bhardwaj A, Addya S, Williams N, Ciment SJ, Cotzia P, Dean JL, Snook A, McNair C, Price M, Hernandez JR, Zhao SG, Birbe R, McCarthy JB, Turley EA, Pienta KJ, Feng FY, Dicker AP, Knudsen KE, Den RB. Thangavel C, et al. Among authors: addya s. Cancer Res. 2017 Feb 15;77(4):982-995. doi: 10.1158/0008-5472.CAN-16-1589. Epub 2016 Dec 6. Cancer Res. 2017. PMID: 27923835 Free PMC article.
Therapeutic Challenge with a CDK 4/6 Inhibitor Induces an RB-Dependent SMAC-Mediated Apoptotic Response in Non-Small Cell Lung Cancer.
Thangavel C, Boopathi E, Liu Y, McNair C, Haber A, Perepelyuk M, Bhardwaj A, Addya S, Ertel A, Shoyele S, Birbe R, Salvino JM, Dicker AP, Knudsen KE, Den RB. Thangavel C, et al. Among authors: addya s. Clin Cancer Res. 2018 Mar 15;24(6):1402-1414. doi: 10.1158/1078-0432.CCR-17-2074. Epub 2018 Jan 8. Clin Cancer Res. 2018. PMID: 29311118 Free PMC article.
Gfi-1 inhibits proliferation and colony formation of p210BCR/ABL-expressing cells via transcriptional repression of STAT 5 and Mcl-1.
Soliera AR, Mariani SA, Audia A, Lidonnici MR, Addya S, Ferrari-Amorotti G, Cattelani S, Manzotti G, Fragliasso V, Peterson L, Perini G, Holyoake TL, Calabretta B. Soliera AR, et al. Among authors: addya s. Leukemia. 2012 Jul;26(7):1555-63. doi: 10.1038/leu.2012.19. Epub 2012 Jan 30. Leukemia. 2012. PMID: 22285998 Free PMC article.
123 results