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Defining the impact of mutation accumulation on replicative lifespan in yeast using cancer-associated mutator phenotypes.
Lee MB, Dowsett IT, Carr DT, Wasko BM, Stanton SG, Chung MS, Ghodsian N, Bode A, Kiflezghi MG, Uppal PA, Grayden KA, Elala YC, Tang TT, Tran NHB, Tran THB, Diep AB, Hope M, Promislow DEL, Kennedy SR, Kaeberlein M, Herr AJ. Lee MB, et al. Among authors: herr aj. Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):3062-3071. doi: 10.1073/pnas.1815966116. Epub 2019 Feb 4. Proc Natl Acad Sci U S A. 2019. PMID: 30718408 Free PMC article.
Somatic mutations in aging, cancer and neurodegeneration.
Kennedy SR, Loeb LA, Herr AJ. Kennedy SR, et al. Among authors: herr aj. Mech Ageing Dev. 2012 Apr;133(4):118-26. doi: 10.1016/j.mad.2011.10.009. Epub 2011 Nov 3. Mech Ageing Dev. 2012. PMID: 22079405 Free PMC article. Review.
DNA replication error-induced extinction of diploid yeast.
Herr AJ, Kennedy SR, Knowels GM, Schultz EM, Preston BD. Herr AJ, et al. Genetics. 2014 Mar;196(3):677-91. doi: 10.1534/genetics.113.160960. Epub 2014 Jan 3. Genetics. 2014. PMID: 24388879 Free PMC article.
Volatility of Mutator Phenotypes at Single Cell Resolution.
Kennedy SR, Schultz EM, Chappell TM, Kohrn B, Knowels GM, Herr AJ. Kennedy SR, et al. Among authors: herr aj. PLoS Genet. 2015 Apr 13;11(4):e1005151. doi: 10.1371/journal.pgen.1005151. eCollection 2015 Apr. PLoS Genet. 2015. PMID: 25868109 Free PMC article.
Loss of vacuolar acidity results in iron-sulfur cluster defects and divergent homeostatic responses during aging in Saccharomyces cerevisiae.
Chen KL, Ven TN, Crane MM, Brunner MLC, Pun AK, Helget KL, Brower K, Chen DE, Doan H, Dillard-Telm JD, Huynh E, Feng YC, Yan Z, Golubeva A, Hsu RA, Knight R, Levin J, Mobasher V, Muir M, Omokehinde V, Screws C, Tunali E, Tran RK, Valdez L, Yang E, Kennedy SR, Herr AJ, Kaeberlein M, Wasko BM. Chen KL, et al. Among authors: herr aj. Geroscience. 2020 Apr;42(2):749-764. doi: 10.1007/s11357-020-00159-3. Epub 2020 Jan 23. Geroscience. 2020. PMID: 31975050 Free PMC article.
36 results