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Pyrrolinone derivatives as a new class of P2X3 receptor antagonists Part 2: Discovery of orally bioavailable compounds.
Tobinaga H, Kameyama T, Asahi K, Horiguchi T, Oohara M, Tada Y, Fuchino K, Jikihara S, Endoh T, Kurihara N, Kanda Y, Ogawa M, Tamura N, Yagi S, Taniguchi E, Takahara Y, Shimada S, Takeyama C, Yamamoto S, Shinohara S, Kai H. Tobinaga H, et al. Among authors: takahara y. Bioorg Med Chem Lett. 2019 Mar 1;29(5):688-693. doi: 10.1016/j.bmcl.2019.01.039. Epub 2019 Feb 1. Bioorg Med Chem Lett. 2019. PMID: 30728111
Pyrrolinone derivatives as a new class of P2X3 receptor antagonists. Part 3: Structure-activity relationships of pyrropyrazolone derivatives.
Tobinaga H, Kameyama T, Asahi K, Horiguchi T, Oohara M, Taoda Y, Hata K, Hasegawa T, Tada Y, Kurihara N, Kanda Y, Yagi S, Tomari M, Tanaka Y, Takahashi F, Taniguchi E, Takahara Y, Shimada S, Takeyama C, Yamamoto S, Shinohara S, Kai H. Tobinaga H, et al. Among authors: takahara y. Bioorg Med Chem Lett. 2020 Dec 15;30(24):127636. doi: 10.1016/j.bmcl.2020.127636. Epub 2020 Oct 22. Bioorg Med Chem Lett. 2020. PMID: 33132115
Generalizable and transportable resting-state neural signatures characterized by functional networks, neurotransmitters, and clinical symptoms in autism.
Itahashi T, Yamashita A, Takahara Y, Yahata N, Aoki YY, Fujino J, Yoshihara Y, Nakamura M, Aoki R, Okimura T, Ohta H, Sakai Y, Takamura M, Ichikawa N, Okada G, Okada N, Kasai K, Tanaka SC, Imamizu H, Kato N, Okamoto Y, Takahashi H, Kawato M, Yamashita O, Hashimoto RI. Itahashi T, et al. Among authors: takahara y. Mol Psychiatry. 2024 Sep 28. doi: 10.1038/s41380-024-02759-3. Online ahead of print. Mol Psychiatry. 2024. PMID: 39342041
315 results