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Pyrrolinone derivatives as a new class of P2X3 receptor antagonists Part 2: Discovery of orally bioavailable compounds.
Tobinaga H, Kameyama T, Asahi K, Horiguchi T, Oohara M, Tada Y, Fuchino K, Jikihara S, Endoh T, Kurihara N, Kanda Y, Ogawa M, Tamura N, Yagi S, Taniguchi E, Takahara Y, Shimada S, Takeyama C, Yamamoto S, Shinohara S, Kai H. Tobinaga H, et al. Among authors: tamura n. Bioorg Med Chem Lett. 2019 Mar 1;29(5):688-693. doi: 10.1016/j.bmcl.2019.01.039. Epub 2019 Feb 1. Bioorg Med Chem Lett. 2019. PMID: 30728111
Dioxotriazine derivatives as a new class of P2X3 receptor antagonists: Identification of a lead and initial SAR studies.
Kai H, Horiguchi T, Kameyama T, Asahi K, Endoh T, Jikihara S, Hasegawa T, Tanaka S, Nozu A, Takeyama C, Tomari M, Takahashi F, Tamura N, Yagi S, Itoh T, Isou Y. Kai H, et al. Among authors: tamura n. Bioorg Med Chem Lett. 2021 Apr 1;37:127833. doi: 10.1016/j.bmcl.2021.127833. Epub 2021 Feb 2. Bioorg Med Chem Lett. 2021. PMID: 33540044
Prediction Characteristics of Oral Absorption Simulation Software Evaluated Using Structurally Diverse Low-Solubility Drugs.
Matsumura N, Hayashi S, Akiyama Y, Ono A, Funaki S, Tamura N, Kimoto T, Jiko M, Haruna Y, Sarashina A, Ishida M, Nishiyama K, Fushimi M, Kojima Y, Yoneda K, Nakanishi M, Kim S, Fujita T, Sugano K. Matsumura N, et al. Among authors: tamura n. J Pharm Sci. 2020 Mar;109(3):1403-1416. doi: 10.1016/j.xphs.2019.12.009. Epub 2019 Dec 18. J Pharm Sci. 2020. PMID: 31863733
Prediction of Oral Drug Absorption in Rats from In Vitro Data.
Akiyama Y, Matsumura N, Ono A, Hayashi S, Funaki S, Tamura N, Kimoto T, Jiko M, Haruna Y, Sarashina A, Ishida M, Nishiyama K, Fushimi M, Kojima Y, Fujita T, Sugano K. Akiyama Y, et al. Among authors: tamura n. Pharm Res. 2023 Feb;40(2):359-373. doi: 10.1007/s11095-022-03173-6. Epub 2022 Feb 15. Pharm Res. 2023. PMID: 35169960
Harmonizing solubility measurement to lower inter-laboratory variance - progress of consortium of biopharmaceutical tools (CoBiTo) in Japan.
Ono A, Matsumura N, Kimoto T, Akiyama Y, Funaki S, Tamura N, Hayashi S, Kojima Y, Fushimi M, Sudaki H, Aihara R, Haruna Y, Jiko M, Iwasaki M, Fujita T, Sugano K. Ono A, et al. Among authors: tamura n. ADMET DMPK. 2019 Aug 5;7(3):183-195. doi: 10.5599/admet.704. eCollection 2019. ADMET DMPK. 2019. PMID: 35350659 Free PMC article.
1,423 results