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Suppressing fatty acid uptake has therapeutic effects in preclinical models of prostate cancer.
Watt MJ, Clark AK, Selth LA, Haynes VR, Lister N, Rebello R, Porter LH, Niranjan B, Whitby ST, Lo J, Huang C, Schittenhelm RB, Anderson KE, Furic L, Wijayaratne PR, Matzaris M, Montgomery MK, Papargiris M, Norden S, Febbraio M, Risbridger GP, Frydenberg M, Nomura DK, Taylor RA. Watt MJ, et al. Sci Transl Med. 2019 Feb 6;11(478):eaau5758. doi: 10.1126/scitranslmed.aau5758. Sci Transl Med. 2019. PMID: 30728288
Hematopoietic cell-restricted deletion of CD36 reduces high-fat diet-induced macrophage infiltration and improves insulin signaling in adipose tissue.
Nicholls HT, Kowalski G, Kennedy DJ, Risis S, Zaffino LA, Watson N, Kanellakis P, Watt MJ, Bobik A, Bonen A, Febbraio M, Lancaster GI, Febbraio MA. Nicholls HT, et al. Among authors: watt mj. Diabetes. 2011 Apr;60(4):1100-10. doi: 10.2337/db10-1353. Epub 2011 Mar 4. Diabetes. 2011. PMID: 21378177 Free PMC article.
Integrated phenotypic and activity-based profiling links Ces3 to obesity and diabetes.
Dominguez E, Galmozzi A, Chang JW, Hsu KL, Pawlak J, Li W, Godio C, Thomas J, Partida D, Niessen S, O'Brien PE, Russell AP, Watt MJ, Nomura DK, Cravatt BF, Saez E. Dominguez E, et al. Among authors: watt mj. Nat Chem Biol. 2014 Feb;10(2):113-21. doi: 10.1038/nchembio.1429. Epub 2013 Dec 22. Nat Chem Biol. 2014. PMID: 24362705 Free PMC article.
Augmented expression and secretion of adipose-derived pigment epithelium-derived factor does not alter local angiogenesis or contribute to the development of systemic metabolic derangements.
Lakeland TV, Borg ML, Matzaris M, Abdelkader A, Evans RG, Watt MJ. Lakeland TV, et al. Among authors: watt mj. Am J Physiol Endocrinol Metab. 2014 Jun 15;306(12):E1367-77. doi: 10.1152/ajpendo.00046.2014. Epub 2014 Apr 22. Am J Physiol Endocrinol Metab. 2014. PMID: 24760990 Free article.
292 results