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An ingestible self-orienting system for oral delivery of macromolecules.
Abramson A, Caffarel-Salvador E, Khang M, Dellal D, Silverstein D, Gao Y, Frederiksen MR, Vegge A, Hubálek F, Water JJ, Friderichsen AV, Fels J, Kirk RK, Cleveland C, Collins J, Tamang S, Hayward A, Landh T, Buckley ST, Roxhed N, Rahbek U, Langer R, Traverso G. Abramson A, et al. Among authors: rahbek u. Science. 2019 Feb 8;363(6427):611-615. doi: 10.1126/science.aau2277. Science. 2019. PMID: 30733413 Free PMC article.
Oral delivery of systemic monoclonal antibodies, peptides and small molecules using gastric auto-injectors.
Abramson A, Frederiksen MR, Vegge A, Jensen B, Poulsen M, Mouridsen B, Jespersen MO, Kirk RK, Windum J, Hubálek F, Water JJ, Fels J, Gunnarsson SB, Bohr A, Straarup EM, Ley MWH, Lu X, Wainer J, Collins J, Tamang S, Ishida K, Hayward A, Herskind P, Buckley ST, Roxhed N, Langer R, Rahbek U, Traverso G. Abramson A, et al. Among authors: rahbek u. Nat Biotechnol. 2022 Jan;40(1):103-109. doi: 10.1038/s41587-021-01024-0. Epub 2021 Aug 30. Nat Biotechnol. 2022. PMID: 34462588 Free PMC article.
A luminal unfolding microneedle injector for oral delivery of macromolecules.
Abramson A, Caffarel-Salvador E, Soares V, Minahan D, Tian RY, Lu X, Dellal D, Gao Y, Kim S, Wainer J, Collins J, Tamang S, Hayward A, Yoshitake T, Lee HC, Fujimoto J, Fels J, Frederiksen MR, Rahbek U, Roxhed N, Langer R, Traverso G. Abramson A, et al. Among authors: rahbek u. Nat Med. 2019 Oct;25(10):1512-1518. doi: 10.1038/s41591-019-0598-9. Epub 2019 Oct 7. Nat Med. 2019. PMID: 31591601 Free PMC article.
A microneedle platform for buccal macromolecule delivery.
Caffarel-Salvador E, Kim S, Soares V, Tian RY, Stern SR, Minahan D, Yona R, Lu X, Zakaria FR, Collins J, Wainer J, Wong J, McManus R, Tamang S, McDonnell S, Ishida K, Hayward A, Liu X, Hubálek F, Fels J, Vegge A, Frederiksen MR, Rahbek U, Yoshitake T, Fujimoto J, Roxhed N, Langer R, Traverso G. Caffarel-Salvador E, et al. Among authors: rahbek u. Sci Adv. 2021 Jan 22;7(4):eabe2620. doi: 10.1126/sciadv.abe2620. Print 2021 Jan. Sci Adv. 2021. PMID: 33523951 Free PMC article.
22 results