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Selected α-pyrones from the plants Cryptocarya novoguineensis (Lauraceae) and Piper methysticum (Piperaceae) with activity against Haemonchus contortus in vitro.
Herath HMPD, Preston S, Jabbar A, Garcia-Bustos J, Addison RS, Hayes S, Rali T, Wang T, Koehler AV, Chang BCH, Hofmann A, Davis RA, Gasser RB. Herath HMPD, et al. Int J Parasitol Drugs Drug Resist. 2019 Apr;9:72-79. doi: 10.1016/j.ijpddr.2018.12.006. Epub 2019 Jan 4. Int J Parasitol Drugs Drug Resist. 2019. PMID: 30739078 Free PMC article.
Phenotypic screening of the 'Kurz-box' of chemicals identifies two compounds (BLK127 and HBK4) with anthelmintic activity in vitro against parasitic larval stages of Haemonchus contortus.
Nguyen LT, Kurz T, Preston S, Brueckmann H, Lungerich B, Herath HMPD, Koehler AV, Wang T, Skálová L, Jabbar A, Gasser RB. Nguyen LT, et al. Among authors: herath hmpd. Parasit Vectors. 2019 Apr 30;12(1):191. doi: 10.1186/s13071-019-3426-7. Parasit Vectors. 2019. PMID: 31039802 Free PMC article.
A suicide inhibitor of nematode trehalose-6-phosphate phosphatases.
Cross M, York M, Długosz E, Straub JH, Biberacher S, Herath HMPD, Logan SA, Kim JS, Gasser RB, Ryan JH, Hofmann A. Cross M, et al. Among authors: herath hmpd. Sci Rep. 2019 Nov 7;9(1):16165. doi: 10.1038/s41598-019-52593-9. Sci Rep. 2019. PMID: 31700060 Free PMC article.
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