Alves C - Search Results

1

Challenging the workhorse: Comparative analysis of eukaryotic micro-organisms for expressing monoclonal antibodies.

Jiang H, Horwitz AA, Wright C, Tai A, Znameroski EA, Tsegaye Y, Warbington H, Bower BS, Alves C, Co C, Jonnalagadda K, Platt D, Walter JM, Natarajan V, Ubersax JA, Cherry JR, Love JC. Jiang H, et al. Among authors: alves c. Biotechnol Bioeng. 2019 Jun;116(6):1449-1462. doi: 10.1002/bit.26951. Epub 2019 Mar 7. Biotechnol Bioeng. 2019. PMID: 30739333 Free PMC article.

2

Leveraging a CHO cell line toolkit to accelerate biotherapeutics into the clinic.

Wright C, Alves C, Kshirsagar R, Pieracci J, Estes S. Wright C, et al. Among authors: alves c. Biotechnol Prog. 2017 Nov;33(6):1468-1475. doi: 10.1002/btpr.2548. Epub 2017 Sep 7. Biotechnol Prog. 2017. PMID: 28842948

3

CHO genome mining for synthetic promoter design.

Johari YB, Brown AJ, Alves CS, Zhou Y, Wright CM, Estes SD, Kshirsagar R, James DC. Johari YB, et al. Among authors: alves cs. J Biotechnol. 2019 Mar 20;294:1-13. doi: 10.1016/j.jbiotec.2019.01.015. Epub 2019 Jan 28. J Biotechnol. 2019. PMID: 30703471 Free article.

4

Integrated cell and process engineering for improved transient production of a "difficult-to-express" fusion protein by CHO cells.

Johari YB, Estes SD, Alves CS, Sinacore MS, James DC. Johari YB, et al. Among authors: alves cs. Biotechnol Bioeng. 2015 Dec;112(12):2527-42. doi: 10.1002/bit.25687. Epub 2015 Sep 7. Biotechnol Bioeng. 2015. PMID: 26126657

5

Debottlenecking protein secretion and reducing protein aggregation in the cellular host.

Zhou Y, Raju R, Alves C, Gilbert A. Zhou Y, et al. Among authors: alves c. Curr Opin Biotechnol. 2018 Oct;53:151-157. doi: 10.1016/j.copbio.2018.01.007. Epub 2018 Feb 3. Curr Opin Biotechnol. 2018. PMID: 29414073 Review.

6

Integration of cell line and process development to overcome the challenge of a difficult to express protein.

Alves CS, Gilbert A, Dalvi S, St Germain B, Xie W, Estes S, Kshirsagar R, Ryll T. Alves CS, et al. Biotechnol Prog. 2015 Sep-Oct;31(5):1201-11. doi: 10.1002/btpr.2091. Epub 2015 May 11. Biotechnol Prog. 2015. PMID: 25919541

7

CHOmics: A web-based tool for multi-omics data analysis and interactive visualization in CHO cell lines.

Lin D, Yalamanchili HB, Zhang X, Lewis NE, Alves CS, Groot J, Arnsdorf J, Bjørn SP, Wulff T, Voldborg BG, Zhou Y, Zhang B. Lin D, et al. PLoS Comput Biol. 2020 Dec 22;16(12):e1008498. doi: 10.1371/journal.pcbi.1008498. eCollection 2020 Dec. PLoS Comput Biol. 2020. PMID: 33351794 Free PMC article.

8

Benchmarking and optimization of a high-throughput sequencing based method for transgene sequence variant analysis in biotherapeutic cell line development.

Groot J, Zhou Y, Marshall E, Cullen P, Carlile T, Lin D, Xu CF, Crisafulli J, Sun C, Casey F, Zhang B, Alves C. Groot J, et al. Among authors: alves c. Biotechnol J. 2021 Aug;16(8):e2000548. doi: 10.1002/biot.202000548. Epub 2021 Jun 3. Biotechnol J. 2021. PMID: 34018310

9

Strategies and Considerations for Improving Expression of "Difficult to Express" Proteins in CHO Cells.

Alves CS, Dobrowsky TM. Alves CS, et al. Methods Mol Biol. 2017;1603:1-23. doi: 10.1007/978-1-4939-6972-2_1. Methods Mol Biol. 2017. PMID: 28493120

10

Implementation of Plate Imaging for Demonstration of Monoclonality in Biologics Manufacturing Development.

Zingaro K, Shaw D, Carson J, Mayer-Bartschmid A, Bender C, Alves C, Mcvey D, Qian NX, Wei Q, Laird MW, Zhu Y, Emmins R, Follit JA, Porter A, Racher AJ, Milne S, Carubelli I, Du Z, Khatri A, Failly M, Broly H, Lee F, Reeser M, Spidel J, Anderson K, Demaria C, Di-Carlo J, Gill J, Lundquist A, Kumar SR, Gill T. Zingaro K, et al. Among authors: alves c. PDA J Pharm Sci Technol. 2018 Jul-Aug;72(4):438-450. doi: 10.5731/pdajpst.2018.008789. Epub 2018 Apr 18. PDA J Pharm Sci Technol. 2018. PMID: 29669815

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