Li Z - Search Results

1

Discovery of Carboline Derivatives as Potent Antifungal Agents for the Treatment of Cryptococcal Meningitis.

Tu J, Li Z, Jiang Y, Ji C, Han G, Wang Y, Liu N, Sheng C. Tu J, et al. Among authors: li z. J Med Chem. 2019 Mar 14;62(5):2376-2389. doi: 10.1021/acs.jmedchem.8b01598. Epub 2019 Feb 22. J Med Chem. 2019. PMID: 30753074

2

Discovery of novel simplified isoxazole derivatives of sampangine as potent anti-cryptococcal agents.

Li Z, Liu N, Tu J, Ji C, Han G, Wang Y, Sheng C. Li Z, et al. Bioorg Med Chem. 2019 Mar 1;27(5):832-840. doi: 10.1016/j.bmc.2019.01.029. Epub 2019 Jan 25. Bioorg Med Chem. 2019. PMID: 30711309

3

Discovery of Simplified Sampangine Derivatives with Potent Antifungal Activities against Cryptococcal Meningitis.

Li Z, Liu N, Tu J, Ji C, Han G, Sheng C. Li Z, et al. ACS Infect Dis. 2019 Aug 9;5(8):1376-1384. doi: 10.1021/acsinfecdis.9b00086. Epub 2019 May 22. ACS Infect Dis. 2019. PMID: 31070884

4

Drug Repurposing of Haloperidol: Discovery of New Benzocyclane Derivatives as Potent Antifungal Agents against Cryptococcosis and Candidiasis.

Ji C, Liu N, Tu J, Li Z, Han G, Li J, Sheng C. Ji C, et al. Among authors: li z, li j. ACS Infect Dis. 2020 May 8;6(5):768-786. doi: 10.1021/acsinfecdis.9b00197. Epub 2019 Oct 8. ACS Infect Dis. 2020. PMID: 31550886

5

Discovery of Novel Fungal Lanosterol 14α-Demethylase (CYP51)/Histone Deacetylase Dual Inhibitors to Treat Azole-Resistant Candidiasis.

Han G, Liu N, Li C, Tu J, Li Z, Sheng C. Han G, et al. Among authors: li c, li z. J Med Chem. 2020 May 28;63(10):5341-5359. doi: 10.1021/acs.jmedchem.0c00102. Epub 2020 May 9. J Med Chem. 2020. PMID: 32347094

6

Novel Carboline Fungal Histone Deacetylase (HDAC) Inhibitors for Combinational Treatment of Azole-Resistant Candidiasis.

Li Z, Tu J, Han G, Liu N, Sheng C. Li Z, et al. J Med Chem. 2021 Jan 28;64(2):1116-1126. doi: 10.1021/acs.jmedchem.0c01763. Epub 2020 Dec 27. J Med Chem. 2021. PMID: 33356256

7

Discovery of Piperidol Derivatives for Combinational Treatment of Azole-Resistant Candidiasis.

Yang W, Tu J, Ji C, Li Z, Han G, Liu N, Li J, Sheng C. Yang W, et al. Among authors: li z, li j. ACS Infect Dis. 2021 Mar 12;7(3):650-660. doi: 10.1021/acsinfecdis.0c00849. Epub 2021 Feb 16. ACS Infect Dis. 2021. PMID: 33593060

8

BET-HDAC Dual Inhibitors for Combinational Treatment of Breast Cancer and Concurrent Candidiasis.

Huang Y, Liu N, Pan Z, Li Z, Sheng C. Huang Y, et al. Among authors: li z. J Med Chem. 2023 Jan 26;66(2):1239-1253. doi: 10.1021/acs.jmedchem.2c01191. Epub 2023 Jan 9. J Med Chem. 2023. PMID: 36622852

9

Target- and prodrug-based design for fungal diseases and cancer-associated fungal infections.

Liu N, Tu J, Huang Y, Yang W, Wang Q, Li Z, Sheng C. Liu N, et al. Among authors: li z. Adv Drug Deliv Rev. 2023 Jun;197:114819. doi: 10.1016/j.addr.2023.114819. Epub 2023 Apr 4. Adv Drug Deliv Rev. 2023. PMID: 37024014 Review.

10

Discovery of BRD4-HDAC Dual Inhibitors with Improved Fungal Selectivity and Potent Synergistic Antifungal Activity against Fluconazole-Resistant Candida albicans.

Li Z, Huang Y, Tu J, Yang W, Liu N, Wang W, Sheng C. Li Z, et al. J Med Chem. 2023 Apr 27;66(8):5950-5964. doi: 10.1021/acs.jmedchem.3c00165. Epub 2023 Apr 10. J Med Chem. 2023. PMID: 37037787

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