Chen L - Search Results

1

Fluorescent Triazole Urea Activity-Based Probes for the Single-Cell Phenotypic Characterization of Staphylococcus aureus.

Chen L, Keller LJ, Cordasco E, Bogyo M, Lentz CS. Chen L, et al. Angew Chem Int Ed Engl. 2019 Apr 16;58(17):5643-5647. doi: 10.1002/anie.201900511. Epub 2019 Mar 22. Angew Chem Int Ed Engl. 2019. PMID: 30768830 Free PMC article.

2

Structural Basis for the Inhibitor and Substrate Specificity of the Unique Fph Serine Hydrolases of Staphylococcus aureus.

Fellner M, Lentz CS, Jamieson SA, Brewster JL, Chen L, Bogyo M, Mace PD. Fellner M, et al. Among authors: chen l. ACS Infect Dis. 2020 Oct 9;6(10):2771-2782. doi: 10.1021/acsinfecdis.0c00503. Epub 2020 Sep 15. ACS Infect Dis. 2020. PMID: 32865965

3

Single-cell chemical proteomics with an activity-based probe: identification of low-copy membrane proteins on primary neurons.

Xu F, Zhao H, Feng X, Chen L, Chen D, Zhang Y, Nan F, Liu J, Liu BF. Xu F, et al. Among authors: chen l, chen d. Angew Chem Int Ed Engl. 2014 Jun 23;53(26):6730-3. doi: 10.1002/anie.201402363. Epub 2014 May 21. Angew Chem Int Ed Engl. 2014. PMID: 24850238

4

Discovery of a novel calcium-sensitive fluorescent probe for α-ketoglutarate.

Gan LL, Chen LH, Nan FJ. Gan LL, et al. Acta Pharmacol Sin. 2017 Dec;38(12):1683-1690. doi: 10.1038/aps.2017.75. Epub 2017 Jul 17. Acta Pharmacol Sin. 2017. PMID: 28713156 Free PMC article.

5

Discovery of GPR84 Fluorogenic Probes Based on a Novel Antagonist for GPR84 Bioimaging.

Xiao Y, Chen J, Li S, Zhang Q, Liu Y, Chen L, Sun Y, Gu M, Xie X, Nan F. Xiao Y, et al. Among authors: chen j, chen l. J Med Chem. 2024 Jul 11;67(13):10875-10890. doi: 10.1021/acs.jmedchem.4c00359. Epub 2024 Jul 1. J Med Chem. 2024. PMID: 38946306

6

High-Throughput Screening Campaign Identified a Potential Small Molecule RXFP3/4 Agonist.

Lin G, Feng Y, Cai X, Zhou C, Shao L, Chen Y, Chen L, Liu Q, Zhou Q, Bathgate RAD, Yang D, Wang MW. Lin G, et al. Among authors: chen l, chen y. Molecules. 2021 Dec 11;26(24):7511. doi: 10.3390/molecules26247511. Molecules. 2021. PMID: 34946593 Free PMC article.

7

Design and Synthesis of 2-Alkylpyrimidine-4,6-diol and 6-Alkylpyridine-2,4-diol as Potent GPR84 Agonists.

Liu Y, Zhang Q, Chen LH, Yang H, Lu W, Xie X, Nan FJ. Liu Y, et al. ACS Med Chem Lett. 2016 Mar 30;7(6):579-83. doi: 10.1021/acsmedchemlett.6b00025. eCollection 2016 Jun 9. ACS Med Chem Lett. 2016. PMID: 27326330 Free PMC article.

8

Modulation of the G-Protein-Coupled Receptor 84 (GPR84) by Agonists and Antagonists.

Chen LH, Zhang Q, Xie X, Nan FJ. Chen LH, et al. J Med Chem. 2020 Dec 24;63(24):15399-15409. doi: 10.1021/acs.jmedchem.0c01378. Epub 2020 Dec 2. J Med Chem. 2020. PMID: 33267584

9

Synthesis and Biological Activity of Tetracyclic Dispiro Core Derivatives of Natural Products Dispirocochlearoids A-C.

Pei J, Wang Y, Shi S, Chen L, Yin J, Nan F. Pei J, et al. Among authors: chen l. Org Lett. 2024 Nov 15;26(45):9654-9658. doi: 10.1021/acs.orglett.4c03358. Epub 2024 Nov 1. Org Lett. 2024. PMID: 39485012

10

Phosphodiesters as GPR84 Antagonists for the Treatment of Ulcerative Colitis.

Chen LH, Zhang Q, Xiao YF, Fang YC, Xie X, Nan FJ. Chen LH, et al. J Med Chem. 2022 Mar 10;65(5):3991-4006. doi: 10.1021/acs.jmedchem.1c01813. Epub 2022 Feb 23. J Med Chem. 2022. PMID: 35195005

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