Belal ASF - Search Results

1

Tackling neuroinflammation and cholinergic deficit in Alzheimer's disease: Multi-target inhibitors of cholinesterases, cyclooxygenase-2 and 15-lipoxygenase.

AlFadly ED, Elzahhar PA, Tramarin A, Elkazaz S, Shaltout H, Abu-Serie MM, Janockova J, Soukup O, Ghareeb DA, El-Yazbi AF, Rafeh RW, Bakkar NZ, Kobeissy F, Iriepa I, Moraleda I, Saudi MNS, Bartolini M, Belal ASF. AlFadly ED, et al. Among authors: belal asf. Eur J Med Chem. 2019 Apr 1;167:161-186. doi: 10.1016/j.ejmech.2019.02.012. Epub 2019 Feb 8. Eur J Med Chem. 2019. PMID: 30771604

2

Novel click modifiable thioquinazolinones as anti-inflammatory agents: Design, synthesis, biological evaluation and docking study.

Moussa G, Alaaeddine R, Alaeddine LM, Nassra R, Belal ASF, Ismail A, El-Yazbi AF, Abdel-Ghany YS, Hazzaa A. Moussa G, et al. Among authors: belal asf. Eur J Med Chem. 2018 Jan 20;144:635-650. doi: 10.1016/j.ejmech.2017.12.065. Epub 2017 Dec 18. Eur J Med Chem. 2018. PMID: 29289887

3

Anti-leishmanial click modifiable thiosemicarbazones: Design, synthesis, biological evaluation and in silico studies.

Temraz MG, Elzahhar PA, El-Din A Bekhit A, Bekhit AA, Labib HF, Belal ASF. Temraz MG, et al. Among authors: belal asf. Eur J Med Chem. 2018 May 10;151:585-600. doi: 10.1016/j.ejmech.2018.04.003. Epub 2018 Apr 3. Eur J Med Chem. 2018. PMID: 29656201

4

Design, synthesis, molecular modeling and anti-proliferative evaluation of novel quinoxaline derivatives as potential DNA intercalators and topoisomerase II inhibitors.

Ibrahim MK, Taghour MS, Metwaly AM, Belal A, Mehany ABM, Elhendawy MA, Radwan MM, Yassin AM, El-Deeb NM, Hafez EE, ElSohly MA, Eissa IH. Ibrahim MK, et al. Eur J Med Chem. 2018 Jul 15;155:117-134. doi: 10.1016/j.ejmech.2018.06.004. Epub 2018 Jun 4. Eur J Med Chem. 2018. PMID: 29885574

5

Shooting three inflammatory targets with a single bullet: Novel multi-targeting anti-inflammatory glitazones.

Elzahhar PA, Alaaeddine R, Ibrahim TM, Nassra R, Ismail A, Chua BSK, Frkic RL, Bruning JB, Wallner N, Knape T, von Knethen A, Labib H, El-Yazbi AF, Belal ASF. Elzahhar PA, et al. Among authors: belal asf. Eur J Med Chem. 2019 Apr 1;167:562-582. doi: 10.1016/j.ejmech.2019.02.034. Epub 2019 Feb 13. Eur J Med Chem. 2019. PMID: 30818268

6

Bioconjugation in Drug Delivery: Practical Perspectives and Future Perceptions.

Elzahhar P, Belal ASF, Elamrawy F, Helal NA, Nounou MI. Elzahhar P, et al. Among authors: belal asf. Methods Mol Biol. 2019;2000:125-182. doi: 10.1007/978-1-4939-9516-5_11. Methods Mol Biol. 2019. PMID: 31148014 Review.

7

Expanding the anticancer potential of 1,2,3-triazoles via simultaneously targeting Cyclooxygenase-2, 15-lipoxygenase and tumor-associated carbonic anhydrases.

Elzahhar PA, Abd El Wahab SM, Elagawany M, Daabees H, Belal ASF, El-Yazbi AF, Eid AH, Alaaeddine R, Hegazy RR, Allam RM, Helmy MW, Bahaa Elgendy, Angeli A, El-Hawash SA, Supuran CT. Elzahhar PA, et al. Among authors: belal asf. Eur J Med Chem. 2020 Aug 15;200:112439. doi: 10.1016/j.ejmech.2020.112439. Epub 2020 May 25. Eur J Med Chem. 2020. PMID: 32485532

8

The Emerging Role of COX-2, 15-LOX and PPARγ in Metabolic Diseases and Cancer: An Introduction to Novel Multi-target Directed Ligands (MTDLs).

Alaaeddine RA, Elzahhar PA, AlZaim I, Abou-Kheir W, Belal ASF, El-Yazbi AF. Alaaeddine RA, et al. Among authors: belal asf. Curr Med Chem. 2021;28(11):2260-2300. doi: 10.2174/0929867327999200820173853. Curr Med Chem. 2021. PMID: 32867639

9

Challenging inflammatory process at molecular, cellular and in vivo levels via some new pyrazolyl thiazolones.

Elzahhar PA, Alaaeddine RA, Nassra R, Ismail A, Labib HF, Temraz MG, Belal ASF, El-Yazbi AF. Elzahhar PA, et al. Among authors: belal asf. J Enzyme Inhib Med Chem. 2021 Dec;36(1):669-684. doi: 10.1080/14756366.2021.1887169. J Enzyme Inhib Med Chem. 2021. PMID: 33618602 Free PMC article.

10

Transforming iodoquinol into broad spectrum anti-tumor leads: Repurposing to modulate redox homeostasis.

Chaaban I, Hafez H, AlZaim I, Tannous C, Ragab H, Hazzaa A, Ketat S, Ghoneim A, Katary M, Abd-Alhaseeb MM, Zouein FA, Albohy A, Amer AN, El-Yazbi AF, Belal ASF. Chaaban I, et al. Among authors: belal asf. Bioorg Chem. 2021 Aug;113:105035. doi: 10.1016/j.bioorg.2021.105035. Epub 2021 May 31. Bioorg Chem. 2021. PMID: 34091287

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