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Dual Inhibition of GSK3β and CDK5 Protects the Cytoskeleton of Neurons from Neuroinflammatory-Mediated Degeneration In Vitro and In Vivo.
Reinhardt L, Kordes S, Reinhardt P, Glatza M, Baumann M, Drexler HCA, Menninger S, Zischinsky G, Eickhoff J, Fröb C, Bhattarai P, Arulmozhivarman G, Marrone L, Janosch A, Adachi K, Stehling M, Anderson EN, Abo-Rady M, Bickle M, Pandey UB, Reimer MM, Kizil C, Schöler HR, Nussbaumer P, Klebl B, Sterneckert JL. Reinhardt L, et al. Among authors: pandey ub. Stem Cell Reports. 2019 Mar 5;12(3):502-517. doi: 10.1016/j.stemcr.2019.01.015. Epub 2019 Feb 14. Stem Cell Reports. 2019. PMID: 30773488 Free PMC article.
Isogenic FUS-eGFP iPSC Reporter Lines Enable Quantification of FUS Stress Granule Pathology that Is Rescued by Drugs Inducing Autophagy.
Marrone L, Poser I, Casci I, Japtok J, Reinhardt P, Janosch A, Andree C, Lee HO, Moebius C, Koerner E, Reinhardt L, Cicardi ME, Hackmann K, Klink B, Poletti A, Alberti S, Bickle M, Hermann A, Pandey UB, Hyman AA, Sterneckert JL. Marrone L, et al. Among authors: pandey ub. Stem Cell Reports. 2018 Feb 13;10(2):375-389. doi: 10.1016/j.stemcr.2017.12.018. Epub 2018 Jan 18. Stem Cell Reports. 2018. PMID: 29358088 Free PMC article.
FUS pathology in ALS is linked to alterations in multiple ALS-associated proteins and rescued by drugs stimulating autophagy.
Marrone L, Drexler HCA, Wang J, Tripathi P, Distler T, Heisterkamp P, Anderson EN, Kour S, Moraiti A, Maharana S, Bhatnagar R, Belgard TG, Tripathy V, Kalmbach N, Hosseinzadeh Z, Crippa V, Abo-Rady M, Wegner F, Poletti A, Troost D, Aronica E, Busskamp V, Weis J, Pandey UB, Hyman AA, Alberti S, Goswami A, Sterneckert J. Marrone L, et al. Among authors: pandey ub. Acta Neuropathol. 2019 Jul;138(1):67-84. doi: 10.1007/s00401-019-01998-x. Epub 2019 Apr 1. Acta Neuropathol. 2019. PMID: 30937520 Free PMC article.
Muscleblind acts as a modifier of FUS toxicity by modulating stress granule dynamics and SMN localization.
Casci I, Krishnamurthy K, Kour S, Tripathy V, Ramesh N, Anderson EN, Marrone L, Grant RA, Oliver S, Gochenaur L, Patel K, Sterneckert J, Gleixner AM, Donnelly CJ, Ruepp MD, Sini AM, Zuccaro E, Pennuto M, Pasinelli P, Pandey UB. Casci I, et al. Among authors: pandey ub. Nat Commun. 2019 Dec 6;10(1):5583. doi: 10.1038/s41467-019-13383-z. Nat Commun. 2019. PMID: 31811140 Free PMC article.
Huntingtin-mediated axonal transport requires arginine methylation by PRMT6.
Migazzi A, Scaramuzzino C, Anderson EN, Tripathy D, Hernández IH, Grant RA, Roccuzzo M, Tosatto L, Virlogeux A, Zuccato C, Caricasole A, Ratovitski T, Ross CA, Pandey UB, Lucas JJ, Saudou F, Pennuto M, Basso M. Migazzi A, et al. Among authors: pandey ub. Cell Rep. 2021 Apr 13;35(2):108980. doi: 10.1016/j.celrep.2021.108980. Cell Rep. 2021. PMID: 33852844 Free PMC article.
Drosha-dependent microRNAs modulate FUS-mediated neurodegeneration in vivo.
Kour S, Fortuna T, Anderson EN, Mawrie D, Bilstein J, Sivasubramanian R, Ward C, Roy R, Rajasundaram D, Sterneckert J, Pandey UB. Kour S, et al. Among authors: pandey ub. Nucleic Acids Res. 2023 Nov 10;51(20):11258-11276. doi: 10.1093/nar/gkad774. Nucleic Acids Res. 2023. PMID: 37791873 Free PMC article.
75 results