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An optimised series of substituted N-phenylpyrrolamides as DNA gyrase B inhibitors.
Tiz DB, Skok Ž, Durcik M, Tomašič T, Mašič LP, Ilaš J, Zega A, Draskovits G, Révész T, Nyerges Á, Pál C, Cruz CD, Tammela P, Žigon D, Kikelj D, Zidar N. Tiz DB, et al. Eur J Med Chem. 2019 Apr 1;167:269-290. doi: 10.1016/j.ejmech.2019.02.004. Epub 2019 Feb 10. Eur J Med Chem. 2019. PMID: 30776691
Developing novel classes of protein kinase CK1δ inhibitors by fusing [1,2,4]triazole with different bicyclic heteroaromatic systems.
Grieco I, Bissaro M, Tiz DB, Perez DI, Perez C, Martinez A, Redenti S, Mariotto E, Bortolozzi R, Viola G, Cozza G, Spalluto G, Moro S, Federico S. Grieco I, et al. Among authors: tiz db. Eur J Med Chem. 2021 Apr 15;216:113331. doi: 10.1016/j.ejmech.2021.113331. Epub 2021 Mar 2. Eur J Med Chem. 2021. PMID: 33721670 Free article.
New N-phenylpyrrolamide inhibitors of DNA gyrase with improved antibacterial activity.
Cotman AE, Fulgheri F, Piga M, Peršolja P, Tiz DB, Skok Ž, Durcik M, Sterle M, Dernovšek J, Cruz CD, Tammela P, Szili PÉ, Daruka L, Pál C, Zega A, Mašič LP, Ilaš J, Tomašič T, Kikelj D, Zidar N. Cotman AE, et al. Among authors: tiz db. RSC Adv. 2024 Sep 6;14(39):28423-28454. doi: 10.1039/d4ra04802d. eCollection 2024 Sep 4. RSC Adv. 2024. PMID: 39247510 Free PMC article.