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Adenosine 2B Receptor Expression on Cancer Cells Promotes Metastasis.
Mittal D, Sinha D, Barkauskas D, Young A, Kalimutho M, Stannard K, Caramia F, Haibe-Kains B, Stagg J, Khanna KK, Loi S, Smyth MJ. Mittal D, et al. Among authors: sinha d. Cancer Res. 2016 Aug 1;76(15):4372-82. doi: 10.1158/0008-5472.CAN-16-0544. Epub 2016 May 24. Cancer Res. 2016. PMID: 27221704
Enhanced dependency of KRAS-mutant colorectal cancer cells on RAD51-dependent homologous recombination repair identified from genetic interactions in Saccharomyces cerevisiae.
Kalimutho M, Bain AL, Mukherjee B, Nag P, Nanayakkara DM, Harten SK, Harris JL, Subramanian GN, Sinha D, Shirasawa S, Srihari S, Burma S, Khanna KK. Kalimutho M, et al. Among authors: sinha d. Mol Oncol. 2017 May;11(5):470-490. doi: 10.1002/1878-0261.12040. Epub 2017 Mar 27. Mol Oncol. 2017. PMID: 28173629 Free PMC article.
Cep55 overexpression causes male-specific sterility in mice by suppressing Foxo1 nuclear retention through sustained activation of PI3K/Akt signaling.
Sinha D, Kalimutho M, Bowles J, Chan AL, Merriner DJ, Bain AL, Simmons JL, Freire R, Lopez JA, Hobbs RM, O'Bryan MK, Khanna KK. Sinha D, et al. FASEB J. 2018 Sep;32(9):4984-4999. doi: 10.1096/fj.201701096RR. Epub 2018 Apr 17. FASEB J. 2018. PMID: 29683733
Collectively, our findings demonstrate that Cep55 overexpression causes change in germ cell proportions and manifests as a Sertoli cell only tubule phenotype, similar to that seen in many azoospermic men.-Sinha, D., Kalimutho, M., Bowles, J., Chan, A.-L., Merriner, …
Collectively, our findings demonstrate that Cep55 overexpression causes change in germ cell proportions and manifests as a Sertoli cell only …
CEP55 is a determinant of cell fate during perturbed mitosis in breast cancer.
Kalimutho M, Sinha D, Jeffery J, Nones K, Srihari S, Fernando WC, Duijf PH, Vennin C, Raninga P, Nanayakkara D, Mittal D, Saunus JM, Lakhani SR, López JA, Spring KJ, Timpson P, Gabrielli B, Waddell N, Khanna KK. Kalimutho M, et al. Among authors: sinha d. EMBO Mol Med. 2018 Sep;10(9):e8566. doi: 10.15252/emmm.201708566. EMBO Mol Med. 2018. PMID: 30108112 Free PMC article.
Mitotic slippage: an old tale with a new twist.
Sinha D, Duijf PHG, Khanna KK. Sinha D, et al. Cell Cycle. 2019 Jan;18(1):7-15. doi: 10.1080/15384101.2018.1559557. Epub 2019 Jan 2. Cell Cycle. 2019. PMID: 30601084 Free PMC article. Review.
Cep55 overexpression promotes genomic instability and tumorigenesis in mice.
Sinha D, Nag P, Nanayakkara D, Duijf PHG, Burgess A, Raninga P, Smits VAJ, Bain AL, Subramanian G, Wall M, Finnie JW, Kalimutho M, Khanna KK. Sinha D, et al. Commun Biol. 2020 Oct 21;3(1):593. doi: 10.1038/s42003-020-01304-6. Commun Biol. 2020. PMID: 33087841 Free PMC article.
1,172 results