Mitchison TJ - Search Results

1

A dynamic view of the proteomic landscape during differentiation of ReNcell VM cells, an immortalized human neural progenitor line.

Song Y, Subramanian K, Berberich MJ, Rodriguez S, Latorre IJ, Luria CM, Everley R, Albers MW, Mitchison TJ, Sorger PK. Song Y, et al. Among authors: mitchison tj. Sci Data. 2019 Feb 19;6:190016. doi: 10.1038/sdata.2019.16. Sci Data. 2019. PMID: 30778261 Free PMC article.

2

Analysis of mitosis and antimitotic drug responses in tumors by in vivo microscopy and single-cell pharmacodynamics.

Orth JD, Kohler RH, Foijer F, Sorger PK, Weissleder R, Mitchison TJ. Orth JD, et al. Among authors: mitchison tj. Cancer Res. 2011 Jul 1;71(13):4608-16. doi: 10.1158/0008-5472.CAN-11-0412. Epub 2011 Jun 28. Cancer Res. 2011. PMID: 21712408 Free PMC article.

3

Single-cell and subcellular pharmacokinetic imaging allows insight into drug action in vivo.

Thurber GM, Yang KS, Reiner T, Kohler RH, Sorger P, Mitchison T, Weissleder R. Thurber GM, et al. Nat Commun. 2013;4:1504. doi: 10.1038/ncomms2506. Nat Commun. 2013. PMID: 23422672 Free PMC article.

4

A High Content Screen in Macrophages Identifies Small Molecule Modulators of STING-IRF3 and NFkB Signaling.

Koch PD, Miller HR, Yu G, Tallarico JA, Sorger PK, Wang Y, Feng Y, Thomas JR, Ross NT, Mitchison T. Koch PD, et al. ACS Chem Biol. 2018 Apr 20;13(4):1066-1081. doi: 10.1021/acschembio.7b01060. Epub 2018 Mar 19. ACS Chem Biol. 2018. PMID: 29553248 Free PMC article.

5

Site occupancy calibration of taxane pharmacology in live cells and tissues.

Pineda JJ, Miller MA, Song Y, Kuhn H, Mikula H, Tallapragada N, Weissleder R, Mitchison TJ. Pineda JJ, et al. Among authors: mitchison tj. Proc Natl Acad Sci U S A. 2018 Nov 27;115(48):E11406-E11414. doi: 10.1073/pnas.1800047115. Epub 2018 Nov 14. Proc Natl Acad Sci U S A. 2018. PMID: 30429313 Free PMC article.

6

Quantitative comparison of a human cancer cell surface proteome between interphase and mitosis.

Özlü N, Qureshi MH, Toyoda Y, Renard BY, Mollaoglu G, Özkan NE, Bulbul S, Poser I, Timm W, Hyman AA, Mitchison TJ, Steen JA. Özlü N, et al. Among authors: mitchison tj. EMBO J. 2015 Jan 13;34(2):251-65. doi: 10.15252/embj.201385162. Epub 2014 Dec 4. EMBO J. 2015. PMID: 25476450 Free PMC article.

7

Computational imaging reveals mitochondrial morphology as a biomarker of cancer phenotype and drug response.

Giedt RJ, Fumene Feruglio P, Pathania D, Yang KS, Kilcoyne A, Vinegoni C, Mitchison TJ, Weissleder R. Giedt RJ, et al. Among authors: mitchison tj. Sci Rep. 2016 Sep 9;6:32985. doi: 10.1038/srep32985. Sci Rep. 2016. PMID: 27609668 Free PMC article.

8

A high-throughput cell migration assay using scratch wound healing, a comparison of image-based readout methods.

Yarrow JC, Perlman ZE, Westwood NJ, Mitchison TJ. Yarrow JC, et al. Among authors: mitchison tj. BMC Biotechnol. 2004 Sep 9;4:21. doi: 10.1186/1472-6750-4-21. BMC Biotechnol. 2004. PMID: 15357872 Free PMC article.

9

Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models.

Silva MC, Ferguson FM, Cai Q, Donovan KA, Nandi G, Patnaik D, Zhang T, Huang HT, Lucente DE, Dickerson BC, Mitchison TJ, Fischer ES, Gray NS, Haggarty SJ. Silva MC, et al. Among authors: mitchison tj. Elife. 2019 Mar 25;8:e45457. doi: 10.7554/eLife.45457. Elife. 2019. PMID: 30907729 Free PMC article.

10

A human organoid system that self-organizes to recapitulate growth and differentiation of a benign mammary tumor.

Florian S, Iwamoto Y, Coughlin M, Weissleder R, Mitchison TJ. Florian S, et al. Among authors: mitchison tj. Proc Natl Acad Sci U S A. 2019 Jun 4;116(23):11444-11453. doi: 10.1073/pnas.1702372116. Epub 2019 May 17. Proc Natl Acad Sci U S A. 2019. PMID: 31101720 Free PMC article.

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