Nephew K - Search Results

1

MicroRNA-196a is regulated by ER and is a prognostic biomarker in ER+ breast cancer.

Milevskiy MJG, Gujral U, Del Lama Marques C, Stone A, Northwood K, Burke LJ, Gee JMW, Nephew K, Clark S, Brown MA. Milevskiy MJG, et al. Among authors: nephew k. Br J Cancer. 2019 Mar;120(6):621-632. doi: 10.1038/s41416-019-0395-8. Epub 2019 Feb 20. Br J Cancer. 2019. PMID: 30783203 Free PMC article.

2

The NEDD8 pathway is required for proteasome-mediated degradation of human estrogen receptor (ER)-alpha and essential for the antiproliferative activity of ICI 182,780 in ERalpha-positive breast cancer cells.

Fan M, Bigsby RM, Nephew KP. Fan M, et al. Mol Endocrinol. 2003 Mar;17(3):356-65. doi: 10.1210/me.2002-0323. Epub 2002 Dec 18. Mol Endocrinol. 2003. PMID: 12554766

3

Epigenetic gene silencing in cancer initiation and progression.

Nephew KP, Huang TH. Nephew KP, et al. Cancer Lett. 2003 Feb 20;190(2):125-33. doi: 10.1016/s0304-3835(02)00511-6. Cancer Lett. 2003. PMID: 12565166 Review.

4

Dominant-negative histone H3 lysine 27 mutant derepresses silenced tumor suppressor genes and reverses the drug-resistant phenotype in cancer cells.

Abbosh PH, Montgomery JS, Starkey JA, Novotny M, Zuhowski EG, Egorin MJ, Moseman AP, Golas A, Brannon KM, Balch C, Huang TH, Nephew KP. Abbosh PH, et al. Cancer Res. 2006 Jun 1;66(11):5582-91. doi: 10.1158/0008-5472.CAN-05-3575. Cancer Res. 2006. PMID: 16740693

5

Diverse gene expression and DNA methylation profiles correlate with differential adaptation of breast cancer cells to the antiestrogens tamoxifen and fulvestrant.

Fan M, Yan PS, Hartman-Frey C, Chen L, Paik H, Oyer SL, Salisbury JD, Cheng AS, Li L, Abbosh PH, Huang TH, Nephew KP. Fan M, et al. Cancer Res. 2006 Dec 15;66(24):11954-66. doi: 10.1158/0008-5472.CAN-06-1666. Cancer Res. 2006. PMID: 17178894

6

Apigenin inhibits antiestrogen-resistant breast cancer cell growth through estrogen receptor-alpha-dependent and estrogen receptor-alpha-independent mechanisms.

Long X, Fan M, Bigsby RM, Nephew KP. Long X, et al. Mol Cancer Ther. 2008 Jul;7(7):2096-108. doi: 10.1158/1535-7163.MCT-07-2350. Mol Cancer Ther. 2008. PMID: 18645020 Free PMC article.

7

Computational analysis of microRNA profiles and their target genes suggests significant involvement in breast cancer antiestrogen resistance.

Xin F, Li M, Balch C, Thomson M, Fan M, Liu Y, Hammond SM, Kim S, Nephew KP. Xin F, et al. Bioinformatics. 2009 Feb 15;25(4):430-4. doi: 10.1093/bioinformatics/btn646. Epub 2008 Dec 17. Bioinformatics. 2009. PMID: 19091772 Free PMC article.

8

Epigenetics and ovarian cancer.

Nephew KP, Balch C, Zhang S, Huang TH. Nephew KP, et al. Cancer Treat Res. 2009;149:131-46. doi: 10.1007/978-0-387-98094-2_6. Cancer Treat Res. 2009. PMID: 19763434 Review. No abstract available.

9

Estrogen receptor-alpha-interacting cytokeratins potentiate the antiestrogenic activity of fulvestrant.

Long X, Fan M, Nephew KP. Long X, et al. Cancer Biol Ther. 2010 Mar 1;9(5):389-96. doi: 10.4161/cbt.9.5.10926. Epub 2010 Mar 11. Cancer Biol Ther. 2010. PMID: 20061804 Free article.

10

Prognosis of hormone-dependent breast cancers: implications of the presence of dysfunctional transcriptional networks activated by insulin via the immune transcription factor T-bet.

McCune K, Bhat-Nakshatri P, Thorat MA, Nephew KP, Badve S, Nakshatri H. McCune K, et al. Among authors: nephew kp. Cancer Res. 2010 Jan 15;70(2):685-96. doi: 10.1158/0008-5472.CAN-09-1530. Epub 2010 Jan 12. Cancer Res. 2010. PMID: 20068169 Free PMC article.

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