Fiorucci S - Search Results

1

Discovery of ((1,2,4-oxadiazol-5-yl)pyrrolidin-3-yl)ureidyl derivatives as selective non-steroidal agonists of the G-protein coupled bile acid receptor-1.

Di Leva FS, Festa C, Carino A, De Marino S, Marchianò S, Di Marino D, Finamore C, Monti MC, Zampella A, Fiorucci S, Limongelli V. Di Leva FS, et al. Among authors: fiorucci s. Sci Rep. 2019 Feb 21;9(1):2504. doi: 10.1038/s41598-019-38840-z. Sci Rep. 2019. PMID: 30792450 Free PMC article.

2

Bile-acid-activated receptors: targeting TGR5 and farnesoid-X-receptor in lipid and glucose disorders.

Fiorucci S, Mencarelli A, Palladino G, Cipriani S. Fiorucci S, et al. Trends Pharmacol Sci. 2009 Nov;30(11):570-80. doi: 10.1016/j.tips.2009.08.001. Epub 2009 Sep 14. Trends Pharmacol Sci. 2009. PMID: 19758712 Review.

3

Solomonsterols A and B from Theonella swinhoei. The first example of C-24 and C-23 sulfated sterols from a marine source endowed with a PXR agonistic activity.

Festa C, De Marino S, D'Auria MV, Bifulco G, Renga B, Fiorucci S, Petek S, Zampella A. Festa C, et al. Among authors: fiorucci s. J Med Chem. 2011 Jan 13;54(1):401-5. doi: 10.1021/jm100968b. Epub 2010 Dec 9. J Med Chem. 2011. PMID: 21141967

4

Discovery of sulfated sterols from marine invertebrates as a new class of marine natural antagonists of farnesoid-X-receptor.

Sepe V, Bifulco G, Renga B, D'Amore C, Fiorucci S, Zampella A. Sepe V, et al. Among authors: fiorucci s. J Med Chem. 2011 Mar 10;54(5):1314-20. doi: 10.1021/jm101336m. Epub 2011 Feb 10. J Med Chem. 2011. PMID: 21309576

5

Theonellasterols and conicasterols from Theonella swinhoei. Novel marine natural ligands for human nuclear receptors.

De Marino S, Ummarino R, D'Auria MV, Chini MG, Bifulco G, Renga B, D'Amore C, Fiorucci S, Debitus C, Zampella A. De Marino S, et al. Among authors: fiorucci s. J Med Chem. 2011 Apr 28;54(8):3065-75. doi: 10.1021/jm200169t. Epub 2011 Apr 5. J Med Chem. 2011. PMID: 21428459

6

Towards new ligands of nuclear receptors. Discovery of malaitasterol A, an unique bis-secosterol from marine sponge Theonella swinhoei.

De Marino S, Sepe V, D'Auria MV, Bifulco G, Renga B, Petek S, Fiorucci S, Zampella A. De Marino S, et al. Among authors: fiorucci s. Org Biomol Chem. 2011 Jul 7;9(13):4856-62. doi: 10.1039/c1ob05378g. Epub 2011 May 16. Org Biomol Chem. 2011. PMID: 21584311

7

Total synthesis and pharmacological characterization of solomonsterol A, a potent marine pregnane-X-receptor agonist endowed with anti-inflammatory activity.

Sepe V, Ummarino R, D'Auria MV, Mencarelli A, D'Amore C, Renga B, Zampella A, Fiorucci S. Sepe V, et al. Among authors: fiorucci s. J Med Chem. 2011 Jul 14;54(13):4590-9. doi: 10.1021/jm200241s. Epub 2011 Jun 3. J Med Chem. 2011. PMID: 21599020

8

Farnesoid X receptor agonist for the treatment of liver and metabolic disorders: focus on 6-ethyl-CDCA.

Fiorucci S, Cipriani S, Mencarelli A, Baldelli F, Bifulco G, Zampella A. Fiorucci S, et al. Mini Rev Med Chem. 2011 Aug;11(9):753-62. doi: 10.2174/138955711796355258. Mini Rev Med Chem. 2011. PMID: 21707532

9

The nuclear receptor FXR regulates hepatic transport and metabolism of glutamine and glutamate.

Renga B, Mencarelli A, Cipriani S, D'Amore C, Zampella A, Monti MC, Distrutti E, Fiorucci S. Renga B, et al. Among authors: fiorucci s. Biochim Biophys Acta. 2011 Nov;1812(11):1522-31. doi: 10.1016/j.bbadis.2011.06.009. Epub 2011 Jul 1. Biochim Biophys Acta. 2011. PMID: 21757002 Free article.

10

Conicasterol E, a small heterodimer partner sparing farnesoid X receptor modulator endowed with a pregnane X receptor agonistic activity, from the marine sponge Theonella swinhoei.

Sepe V, Ummarino R, D'Auria MV, Chini MG, Bifulco G, Renga B, D'Amore C, Debitus C, Fiorucci S, Zampella A. Sepe V, et al. Among authors: fiorucci s. J Med Chem. 2012 Jan 12;55(1):84-93. doi: 10.1021/jm201004p. Epub 2011 Dec 14. J Med Chem. 2012. PMID: 22126372

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