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Recruitment of RNA Polymerase II to Metabolic Gene Promoters Is Inhibited in the Failing Heart Possibly Through PGC-1α (Peroxisome Proliferator-Activated Receptor-γ Coactivator-1α) Dysregulation.
Bhat S, Chin A, Shirakabe A, Ikeda Y, Ikeda S, Zhai P, Hsu CP, Sayed D, Abdellatif M, Byun J, Schesing K, Tang F, Tian Y, Babu G, Ralda G, Warren JS, Cho J, Sadoshima J, Oka SI. Bhat S, et al. Among authors: tian y. Circ Heart Fail. 2019 Mar;12(3):e005529. doi: 10.1161/CIRCHEARTFAILURE.118.005529. Circ Heart Fail. 2019. PMID: 30798619 Free PMC article.
Suppression of autophagy induces senescence in the heart.
Zhai P, Sung EA, Shiheido-Watanabe Y, Takayama K, Tian Y, Sadoshima J. Zhai P, et al. Among authors: tian y. J Mol Cell Cardiol. 2024 Oct;195:83-96. doi: 10.1016/j.yjmcc.2024.08.001. Epub 2024 Aug 6. J Mol Cell Cardiol. 2024. PMID: 39117176 Free article.
Alk3/Bmpr1a receptor is required for development of the atrioventricular canal into valves and annulus fibrosus.
Gaussin V, Morley GE, Cox L, Zwijsen A, Vance KM, Emile L, Tian Y, Liu J, Hong C, Myers D, Conway SJ, Depre C, Mishina Y, Behringer RR, Hanks MC, Schneider MD, Huylebroeck D, Fishman GI, Burch JB, Vatner SF. Gaussin V, et al. Among authors: tian y. Circ Res. 2005 Aug 5;97(3):219-26. doi: 10.1161/01.RES.0000177862.85474.63. Epub 2005 Jul 21. Circ Res. 2005. PMID: 16037571 Free PMC article.
Proteasome inhibition decreases cardiac remodeling after initiation of pressure overload.
Hedhli N, Lizano P, Hong C, Fritzky LF, Dhar SK, Liu H, Tian Y, Gao S, Madura K, Vatner SF, Depre C. Hedhli N, et al. Among authors: tian y. Am J Physiol Heart Circ Physiol. 2008 Oct;295(4):H1385-93. doi: 10.1152/ajpheart.00532.2008. Epub 2008 Aug 1. Am J Physiol Heart Circ Physiol. 2008. PMID: 18676687 Free PMC article.
Calorie restriction can reverse, as well as prevent, aging cardiomyopathy.
Yan L, Gao S, Ho D, Park M, Ge H, Wang C, Tian Y, Lai L, De Lorenzo MS, Vatner DE, Vatner SF. Yan L, et al. Among authors: tian y. Age (Dordr). 2013 Dec;35(6):2177-82. doi: 10.1007/s11357-012-9508-5. Epub 2013 Jan 20. Age (Dordr). 2013. PMID: 23334601 Free PMC article. Review.
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