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Page 1
Nanog regulates Pou3f1 expression at the exit from pluripotency during gastrulation.
Barral A, Rollan I, Sanchez-Iranzo H, Jawaid W, Badia-Careaga C, Menchero S, Gomez MJ, Torroja C, Sanchez-Cabo F, Göttgens B, Manzanares M, Sainz de Aja J. Barral A, et al. Among authors: sainz de aja j. Biol Open. 2019 Dec 2;8(11):bio046367. doi: 10.1242/bio.046367. Biol Open. 2019. PMID: 31791948 Free PMC article.
Transitions in cell potency during early mouse development are driven by Notch.
Menchero S, Rollan I, Lopez-Izquierdo A, Andreu MJ, Sainz de Aja J, Kang M, Adan J, Benedito R, Rayon T, Hadjantonakis AK, Manzanares M. Menchero S, et al. Among authors: sainz de aja j. Elife. 2019 Apr 8;8:e42930. doi: 10.7554/eLife.42930. Elife. 2019. PMID: 30958266 Free PMC article.
Transient fibrosis resolves via fibroblast inactivation in the regenerating zebrafish heart.
Sánchez-Iranzo H, Galardi-Castilla M, Sanz-Morejón A, González-Rosa JM, Costa R, Ernst A, Sainz de Aja J, Langa X, Mercader N. Sánchez-Iranzo H, et al. Among authors: sainz de aja j. Proc Natl Acad Sci U S A. 2018 Apr 17;115(16):4188-4193. doi: 10.1073/pnas.1716713115. Epub 2018 Apr 2. Proc Natl Acad Sci U S A. 2018. PMID: 29610343 Free PMC article.
Air-liquid interface culture promotes maturation and allows environmental exposure of pluripotent stem cell-derived alveolar epithelium.
Abo KM, Sainz de Aja J, Lindstrom-Vautrin J, Alysandratos KD, Richards A, Garcia-de-Alba C, Huang J, Hix OT, Werder RB, Bullitt E, Hinds A, Falconer I, Villacorta-Martin C, Jaenisch R, Kim CF, Kotton DN, Wilson AA. Abo KM, et al. Among authors: sainz de aja j. JCI Insight. 2022 Mar 22;7(6):e155589. doi: 10.1172/jci.insight.155589. JCI Insight. 2022. PMID: 35315362 Free PMC article.
Alveolar progenitor cells and the origin of lung cancer.
Sainz de Aja J, Dost AFM, Kim CF. Sainz de Aja J, et al. J Intern Med. 2021 May;289(5):629-635. doi: 10.1111/joim.13201. Epub 2020 Dec 19. J Intern Med. 2021. PMID: 33340175 Free PMC article. Review.
May the (Mechanical) Force Be with AT2.
Sainz de Aja J, Kim CF. Sainz de Aja J, et al. Cell. 2020 Jan 9;180(1):20-22. doi: 10.1016/j.cell.2019.12.020. Cell. 2020. PMID: 31951518 Free PMC article.
SARS-CoV-2 infection of primary human lung epithelium for COVID-19 modeling and drug discovery.
Mulay A, Konda B, Garcia G Jr, Yao C, Beil S, Sen C, Purkayastha A, Kolls JK, Pociask DA, Pessina P, de Aja JS, Garcia-de-Alba C, Kim CF, Gomperts B, Arumugaswami V, Stripp BR. Mulay A, et al. Among authors: de aja js. bioRxiv [Preprint]. 2020 Jun 29:2020.06.29.174623. doi: 10.1101/2020.06.29.174623. bioRxiv. 2020. Update in: Cell Rep. 2021 May 4;35(5):109055. doi: 10.1016/j.celrep.2021.109055 PMID: 32637946 Free PMC article. Updated. Preprint.
Organoids Model Transcriptional Hallmarks of Oncogenic KRAS Activation in Lung Epithelial Progenitor Cells.
Dost AFM, Moye AL, Vedaie M, Tran LM, Fung E, Heinze D, Villacorta-Martin C, Huang J, Hekman R, Kwan JH, Blum BC, Louie SM, Rowbotham SP, Sainz de Aja J, Piper ME, Bhetariya PJ, Bronson RT, Emili A, Mostoslavsky G, Fishbein GA, Wallace WD, Krysan K, Dubinett SM, Yanagawa J, Kotton DN, Kim CF. Dost AFM, et al. Among authors: sainz de aja j. Cell Stem Cell. 2020 Oct 1;27(4):663-678.e8. doi: 10.1016/j.stem.2020.07.022. Epub 2020 Sep 4. Cell Stem Cell. 2020. PMID: 32891189 Free PMC article.