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Hydroxy-substituted trans-cinnamoyl derivatives as multifunctional tools in the context of Alzheimer's disease.
De Simone A, Bartolini M, Baschieri A, Apperley KYP, Chen HH, Guardigni M, Montanari S, Kobrlova T, Soukup O, Valgimigli L, Andrisano V, Keillor JW, Basso M, Milelli A. De Simone A, et al. Among authors: kobrlova t. Eur J Med Chem. 2017 Oct 20;139:378-389. doi: 10.1016/j.ejmech.2017.07.058. Epub 2017 Jul 25. Eur J Med Chem. 2017. PMID: 28810189
In vitro and in silico Evaluation of Non-Quaternary Reactivators of AChE as Antidotes of Organophosphorus Poisoning - a New Hope or a Blind Alley?
Soukup O, Korabecny J, Malinak D, Nepovimova E, Pham NL, Musilek K, Hrabinova M, Hepnarova V, Dolezal R, Pavek P, Jost P, Kobrlova T, Jankockova J, Gorecki L, Psotka M, Nguyen TD, Box K, Outhwaite B, Ceckova M, Sorf A, Jun D, Kuca K. Soukup O, et al. Among authors: kobrlova t. Med Chem. 2018;14(3):281-292. doi: 10.2174/1573406414666180112105657. Med Chem. 2018. PMID: 29332594
Orexin supplementation in narcolepsy treatment: A review.
Nepovimova E, Janockova J, Misik J, Kubik S, Stuchlik A, Vales K, Korabecny J, Mezeiova E, Dolezal R, Soukup O, Kobrlova T, Pham NL, Nguyen TD, Konecny J, Kuca K. Nepovimova E, et al. Among authors: kobrlova t. Med Res Rev. 2019 May;39(3):961-975. doi: 10.1002/med.21550. Epub 2018 Nov 14. Med Res Rev. 2019. PMID: 30426515 Review.
Novel Sustainable-by-Design HDAC Inhibitors for the Treatment of Alzheimer's Disease.
Soares Romeiro LA, da Costa Nunes JL, de Oliveira Miranda C, Simões Heyn Roth Cardoso G, de Oliveira AS, Gandini A, Kobrlova T, Soukup O, Rossi M, Senger J, Jung M, Gervasoni S, Vistoli G, Petralla S, Massenzio F, Monti B, Bolognesi ML. Soares Romeiro LA, et al. Among authors: kobrlova t. ACS Med Chem Lett. 2019 Mar 29;10(4):671-676. doi: 10.1021/acsmedchemlett.9b00071. eCollection 2019 Apr 11. ACS Med Chem Lett. 2019. PMID: 30996816 Free PMC article.
New Dual Small Molecules for Alzheimer's Disease Therapy Combining Histamine H3 Receptor (H3R) Antagonism and Calcium Channels Blockade with Additional Cholinesterase Inhibition.
Malek R, Arribas RL, Palomino-Antolin A, Totoson P, Demougeot C, Kobrlova T, Soukup O, Iriepa I, Moraleda I, Diez-Iriepa D, Godyń J, Panek D, Malawska B, Głuch-Lutwin M, Mordyl B, Siwek A, Chabchoub F, Marco-Contelles J, Kiec-Kononowicz K, Egea J, de Los Ríos C, Ismaili L. Malek R, et al. Among authors: kobrlova t. J Med Chem. 2019 Dec 26;62(24):11416-11422. doi: 10.1021/acs.jmedchem.9b00937. Epub 2019 Dec 5. J Med Chem. 2019. PMID: 31724859
30 results