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Differential metabolism of clinically-relevant progestogens in cell lines and tissue: Implications for biological mechanisms.
Skosana SB, Woodland JG, Cartwright M, Enfield K, Komane M, Louw-du Toit R, van der Spuy Z, Avenant C, Africander D, Storbeck KH, Hapgood JP. Skosana SB, et al. Among authors: avenant c. J Steroid Biochem Mol Biol. 2019 May;189:145-153. doi: 10.1016/j.jsbmb.2019.02.010. Epub 2019 Feb 26. J Steroid Biochem Mol Biol. 2019. PMID: 30822501 Free PMC article.
Glucocorticoid-independent repression of tumor necrosis factor (TNF) alpha-stimulated interleukin (IL)-6 expression by the glucocorticoid receptor: a potential mechanism for protection against an excessive inflammatory response.
Verhoog NJ, Du Toit A, Avenant C, Hapgood JP. Verhoog NJ, et al. Among authors: avenant c. J Biol Chem. 2011 Jun 3;286(22):19297-310. doi: 10.1074/jbc.M110.193672. Epub 2011 Apr 7. J Biol Chem. 2011. PMID: 21474440 Free PMC article.
The injectable-only contraceptive medroxyprogesterone acetate, unlike norethisterone acetate and progesterone, regulates inflammatory genes in endocervical cells via the glucocorticoid receptor.
Govender Y, Avenant C, Verhoog NJ, Ray RM, Grantham NJ, Africander D, Hapgood JP. Govender Y, et al. Among authors: avenant c. PLoS One. 2014 May 19;9(5):e96497. doi: 10.1371/journal.pone.0096497. eCollection 2014. PLoS One. 2014. PMID: 24840644 Free PMC article.
23 results