Moreno-Vargas AJ - Search Results

1

Exploring substituent diversity on pyrrolidine-aryltriazole iminosugars: Structural basis of β-glucocerebrosidase inhibition.

Martínez-Bailén M, Carmona AT, Patterson-Orazem AC, Lieberman RL, Ide D, Kubo M, Kato A, Robina I, Moreno-Vargas AJ. Martínez-Bailén M, et al. Bioorg Chem. 2019 May;86:652-664. doi: 10.1016/j.bioorg.2019.02.025. Epub 2019 Feb 12. Bioorg Chem. 2019. PMID: 30825709

2

New leads for selective inhibitors of alpha-L-fucosidases. Synthesis and glycosidase inhibitory activities of [(2R,3S,4R)-3,4-dihydroxypyrrolidin-2-yl]furan derivatives.

Robina I, Moreno-Vargas AJ, Fernández-Bolaños JG, Fuentes J, Demange R, Vogel P. Robina I, et al. Bioorg Med Chem Lett. 2001 Sep 17;11(18):2555-9. doi: 10.1016/s0960-894x(01)00497-8. Bioorg Med Chem Lett. 2001. PMID: 11549468

3

Synthesis of [(2S,3S,4R)-3,4-dihydroxypyrrolidin-2-yl]-5-methylfuran-4-carboxylic acid derivatives: new leads as selective beta-galactosidase inhibitors.

Moreno-Vargas AJ, Demange R, Fuentes J, Robina I, Vogel P. Moreno-Vargas AJ, et al. Bioorg Med Chem Lett. 2002 Sep 2;12(17):2335-9. doi: 10.1016/s0960-894x(02)00397-9. Bioorg Med Chem Lett. 2002. PMID: 12161128

4

Hetaryleneaminopolyols and hetarylenecarbopeptoids: a new type of glyco- and peptidomimetics. Syntheses and studies on solution conformation and dynamics.

Moreno-Vargas AJ, Jiménez-Barbero J, Robina I. Moreno-Vargas AJ, et al. J Org Chem. 2003 May 30;68(11):4138-50. doi: 10.1021/jo026631o. J Org Chem. 2003. PMID: 12762712

5

Synthesis of d- and l-2,3-trans-3,4-cis-4,5-trans-3,4-dihydroxy-5-hydroxymethylproline and tripeptides containing them.

Moreno-Vargas AJ, Robina I, Petricci E, Vogel P. Moreno-Vargas AJ, et al. J Org Chem. 2004 Jun 25;69(13):4487-91. doi: 10.1021/jo049637h. J Org Chem. 2004. PMID: 15202906

6

Glycosidase inhibitors as potential HIV entry inhibitors?

Robina I, Moreno-Vargas AJ, Carmona AT, Vogel P. Robina I, et al. Curr Drug Metab. 2004 Aug;5(4):329-61. doi: 10.2174/1389200043335513. Curr Drug Metab. 2004. PMID: 15320705 Review.

7

Stereoselective synthesis of (2S,3S,4R,5S)-5-methylpyrrolidine-3,4-diol derivatives that are highly selective alpha-L-fucosidase inhibitors.

Moreno-Vargas AJ, Carmona AT, Mora F, Vogel P, Robina I. Moreno-Vargas AJ, et al. Chem Commun (Camb). 2005 Oct 21;(39):4949-51. doi: 10.1039/b508855k. Epub 2005 Sep 8. Chem Commun (Camb). 2005. PMID: 16205810

8

Synthesis and anti-HIV activity of trivalent CD4-mimetic miniproteins.

Li H, Guan Y, Szczepanska A, Moreno-Vargas AJ, Carmona AT, Robina I, Lewis GK, Wang LX. Li H, et al. Bioorg Med Chem. 2007 Jun 15;15(12):4220-8. doi: 10.1016/j.bmc.2007.03.064. Epub 2007 Mar 24. Bioorg Med Chem. 2007. PMID: 17412600

9

Synthesis and conformational analysis of novel trimeric maleimide cross-linking reagents.

Szczepanska A, Espartero JL, Moreno-Vargas AJ, Carmona AT, Robina I, Remmert S, Parish C. Szczepanska A, et al. J Org Chem. 2007 Aug 31;72(18):6776-85. doi: 10.1021/jo0709293. Epub 2007 Aug 4. J Org Chem. 2007. PMID: 17676908

10

Synthesis of novel pyrrolidine 3,4-diol derivatives as inhibitors of alpha-L-fucosidases.

Moreno-Clavijo E, Carmona AT, Vera-Ayoso Y, Moreno-Vargas AJ, Bello C, Vogel P, Robina I. Moreno-Clavijo E, et al. Org Biomol Chem. 2009 Mar 21;7(6):1192-202. doi: 10.1039/b819867e. Epub 2009 Feb 3. Org Biomol Chem. 2009. PMID: 19262940

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