Murphy JW - Search Results

1

Characterization, Dynamics, and Mechanism of CXCR4 Antagonists on a Constitutively Active Mutant.

Rosenberg EM Jr, Harrison RES, Tsou LK, Drucker N, Humphries B, Rajasekaran D, Luker KE, Wu CH, Song JS, Wang CJ, Murphy JW, Cheng YC, Shia KS, Luker GD, Morikis D, Lolis EJ. Rosenberg EM Jr, et al. Among authors: murphy jw. Cell Chem Biol. 2019 May 16;26(5):662-673.e7. doi: 10.1016/j.chembiol.2019.01.012. Epub 2019 Feb 28. Cell Chem Biol. 2019. PMID: 30827936 Free PMC article.

2

The N-terminal length and side-chain composition of CXCL13 affect crystallization, structure and functional activity.

Rosenberg EM Jr, Herrington J, Rajasekaran D, Murphy JW, Pantouris G, Lolis EJ. Rosenberg EM Jr, et al. Among authors: murphy jw. Acta Crystallogr D Struct Biol. 2020 Oct 1;76(Pt 10):1033-1049. doi: 10.1107/S2059798320011687. Epub 2020 Sep 25. Acta Crystallogr D Struct Biol. 2020. PMID: 33021505 Free PMC article.

3

Heterologous quaternary structure of CXCL12 and its relationship to the CC chemokine family.

Murphy JW, Yuan H, Kong Y, Xiong Y, Lolis EJ. Murphy JW, et al. Proteins. 2010 Apr;78(5):1331-7. doi: 10.1002/prot.22666. Proteins. 2010. PMID: 20077567 Free PMC article. No abstract available.

4

High-Throughput Screening of a Functional Human CXCL12-CXCR4 Signaling Axis in a Genetically Modified S. cerevisiae: Discovery of a Novel Up-Regulator of CXCR4 Activity.

Murphy JW, Rajasekaran D, Merkel J, Skeens E, Keeler C, Hodsdon ME, Lisi GP, Lolis E. Murphy JW, et al. Front Mol Biosci. 2020 Jul 16;7:164. doi: 10.3389/fmolb.2020.00164. eCollection 2020. Front Mol Biosci. 2020. PMID: 32766282 Free PMC article.

5

Structural and functional basis of CXCL12 (stromal cell-derived factor-1 alpha) binding to heparin.

Murphy JW, Cho Y, Sachpatzidis A, Fan C, Hodsdon ME, Lolis E. Murphy JW, et al. J Biol Chem. 2007 Mar 30;282(13):10018-10027. doi: 10.1074/jbc.M608796200. Epub 2007 Jan 29. J Biol Chem. 2007. PMID: 17264079 Free PMC article.

6

Unraveling the mechanism of recognition of the 3' splice site of the adenovirus major late promoter intron by the alternative splicing factor PUF60.

Hsiao HT, Crichlow GV, Murphy JW, Folta-Stogniew EJ, Lolis EJ, Braddock DT. Hsiao HT, et al. Among authors: murphy jw. PLoS One. 2020 Nov 30;15(11):e0242725. doi: 10.1371/journal.pone.0242725. eCollection 2020. PLoS One. 2020. PMID: 33253191 Free PMC article.

7

Two independent histidines, one in human prolactin and one in its receptor, are critical for pH-dependent receptor recognition and activation.

Kulkarni MV, Tettamanzi MC, Murphy JW, Keeler C, Myszka DG, Chayen NE, Lolis EJ, Hodsdon ME. Kulkarni MV, et al. Among authors: murphy jw. J Biol Chem. 2010 Dec 3;285(49):38524-33. doi: 10.1074/jbc.M110.172072. Epub 2010 Sep 30. J Biol Chem. 2010. PMID: 20889499 Free PMC article.

8

A structurally preserved allosteric site in the MIF superfamily affects enzymatic activity and CD74 activation in D-dopachrome tautomerase.

Chen E, Reiss K, Shah D, Manjula R, Allen B, Murphy EL, Murphy JW, Batista VS, Bhandari V, Lolis EJ, Lisi GP. Chen E, et al. Among authors: murphy jw. J Biol Chem. 2021 Sep;297(3):101061. doi: 10.1016/j.jbc.2021.101061. Epub 2021 Aug 9. J Biol Chem. 2021. PMID: 34384784 Free PMC article.

9

CD44 is the signaling component of the macrophage migration inhibitory factor-CD74 receptor complex.

Shi X, Leng L, Wang T, Wang W, Du X, Li J, McDonald C, Chen Z, Murphy JW, Lolis E, Noble P, Knudson W, Bucala R. Shi X, et al. Among authors: murphy jw. Immunity. 2006 Oct;25(4):595-606. doi: 10.1016/j.immuni.2006.08.020. Immunity. 2006. PMID: 17045821 Free PMC article.

10

Structural studies of cerebral cavernous malformations 2 (CCM2) reveal a folded helical domain at its C-terminus.

Fisher OS, Zhang R, Li X, Murphy JW, Demeler B, Boggon TJ. Fisher OS, et al. Among authors: murphy jw. FEBS Lett. 2013 Jan 31;587(3):272-7. doi: 10.1016/j.febslet.2012.12.011. Epub 2012 Dec 22. FEBS Lett. 2013. PMID: 23266514 Free PMC article.

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