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Concurrent SOS1 and MEK suppression inhibits signaling and growth of NF1-null melanoma.
Marasco M, Kumar D, Seale T, Borrego SG, Kaplun E, Aricescu I, Cole S, Qeriqi B, Qiu J, Chen X, Bahr A, Fidele D, Hofmann MH, Gerlach D, Savarese F, Merghoub T, Wolchok JD, Yao Z, de Stanchina E, Solit D, Misale S, Rosen N. Marasco M, et al. Among authors: kaplun e. Cell Rep Med. 2024 Nov 19;5(11):101818. doi: 10.1016/j.xcrm.2024.101818. Epub 2024 Nov 1. Cell Rep Med. 2024. PMID: 39488215 Free PMC article.
Molecular Characterization of Acquired Resistance to KRASG12C-EGFR Inhibition in Colorectal Cancer.
Yaeger R, Mezzadra R, Sinopoli J, Bian Y, Marasco M, Kaplun E, Gao Y, Zhao H, Paula ADC, Zhu Y, Perez AC, Chadalavada K, Tse E, Chowdhry S, Bowker S, Chang Q, Qeriqi B, Weigelt B, Nanjangud GJ, Berger MF, Der-Torossian H, Anderes K, Socci ND, Shia J, Riely GJ, Murciano-Goroff YR, Li BT, Christensen JG, Reis-Filho JS, Solit DB, de Stanchina E, Lowe SW, Rosen N, Misale S. Yaeger R, et al. Among authors: kaplun e. Cancer Discov. 2023 Jan 9;13(1):41-55. doi: 10.1158/2159-8290.CD-22-0405. Cancer Discov. 2023. PMID: 36355783 Free PMC article.
IL1R1 is required for celastrol's leptin-sensitization and antiobesity effects.
Feng X, Guan D, Auen T, Choi JW, Salazar Hernández MA, Lee J, Chun H, Faruk F, Kaplun E, Herbert Z, Copps KD, Ozcan U. Feng X, et al. Among authors: kaplun e. Nat Med. 2019 Apr;25(4):575-582. doi: 10.1038/s41591-019-0358-x. Epub 2019 Mar 4. Nat Med. 2019. PMID: 30833749 Free PMC article.
17 results