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Acoustic Mist Ionization Platform for Direct and Contactless Ultrahigh-Throughput Mass Spectrometry Analysis of Liquid Samples.
Sinclair I, Bachman M, Addison D, Rohman M, Murray DC, Davies G, Mouchet E, Tonge ME, Stearns RG, Ghislain L, Datwani SS, Majlof L, Hall E, Jones GR, Hoyes E, Olechno J, Ellson RN, Barran PE, Pringle SD, Morris MR, Wingfield J. Sinclair I, et al. Among authors: davies g. Anal Chem. 2019 Mar 19;91(6):3790-3794. doi: 10.1021/acs.analchem.9b00142. Epub 2019 Mar 11. Anal Chem. 2019. PMID: 30835099
Design and synthesis of novel lactate dehydrogenase A inhibitors by fragment-based lead generation.
Ward RA, Brassington C, Breeze AL, Caputo A, Critchlow S, Davies G, Goodwin L, Hassall G, Greenwood R, Holdgate GA, Mrosek M, Norman RA, Pearson S, Tart J, Tucker JA, Vogtherr M, Whittaker D, Wingfield J, Winter J, Hudson K. Ward RA, et al. Among authors: davies g. J Med Chem. 2012 Apr 12;55(7):3285-306. doi: 10.1021/jm201734r. Epub 2012 Mar 26. J Med Chem. 2012. PMID: 22417091
AZD9496: An Oral Estrogen Receptor Inhibitor That Blocks the Growth of ER-Positive and ESR1-Mutant Breast Tumors in Preclinical Models.
Weir HM, Bradbury RH, Lawson M, Rabow AA, Buttar D, Callis RJ, Curwen JO, de Almeida C, Ballard P, Hulse M, Donald CS, Feron LJ, Karoutchi G, MacFaul P, Moss T, Norman RA, Pearson SE, Tonge M, Davies G, Walker GE, Wilson Z, Rowlinson R, Powell S, Sadler C, Richmond G, Ladd B, Pazolli E, Mazzola AM, D'Cruz C, De Savi C. Weir HM, et al. Among authors: davies g. Cancer Res. 2016 Jun 1;76(11):3307-18. doi: 10.1158/0008-5472.CAN-15-2357. Epub 2016 Mar 28. Cancer Res. 2016. PMID: 27020862
High-Throughput Mechanism of Inhibition.
Davies G, Semple H, McCandless M, Cairns J, Holdgate GA. Davies G, et al. SLAS Discov. 2021 Feb;26(2):248-256. doi: 10.1177/2472555220983809. SLAS Discov. 2021. PMID: 33482076 Free article.
Biophysical methods in early drug discovery.
Holdgate G, Embrey K, Milbradt A, Davies G. Holdgate G, et al. Among authors: davies g. ADMET DMPK. 2019 Dec 11;7(4):222-241. doi: 10.5599/admet.733. eCollection 2019. ADMET DMPK. 2019. PMID: 35359617 Free PMC article. Review.
3,575 results