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Drug Repurposing: The Anthelmintics Niclosamide and Nitazoxanide Are Potent TMEM16A Antagonists That Fully Bronchodilate Airways.
Miner K, Labitzke K, Liu B, Wang P, Henckels K, Gaida K, Elliott R, Chen JJ, Liu L, Leith A, Trueblood E, Hensley K, Xia XZ, Homann O, Bennett B, Fiorino M, Whoriskey J, Yu G, Escobar S, Wong M, Born TL, Budelsky A, Comeau M, Smith D, Phillips J, Johnston JA, McGivern JG, Weikl K, Powers D, Kunzelmann K, Mohn D, Hochheimer A, Sullivan JK. Miner K, et al. Among authors: henckels k. Front Pharmacol. 2019 Feb 14;10:51. doi: 10.3389/fphar.2019.00051. eCollection 2019. Front Pharmacol. 2019. PMID: 30837866 Free PMC article.
A closed, autologous bioprocess optimized for TCR-T cell therapies.
Liu Y, Zah E, Arbelaez C, Kim H, Gros E, Buck R, Cox K, Kim S, Kopp M, Henckels K, Stevens J. Liu Y, et al. Among authors: henckels k. Biotechnol Bioeng. 2023 Jul;120(7):1809-1821. doi: 10.1002/bit.28389. Epub 2023 Apr 7. Biotechnol Bioeng. 2023. PMID: 37027315