Leach AG - Search Results

1

Enhancing the kinetics of hydrazone exchange processes: an experimental and computational study.

Higgs PL, Ruiz-Sanchez AJ, Dalmina M, Horrocks BR, Leach AG, Fulton DA. Higgs PL, et al. Among authors: leach ag. Org Biomol Chem. 2019 Mar 20;17(12):3218-3224. doi: 10.1039/c9ob00058e. Org Biomol Chem. 2019. PMID: 30840013

2

A Lewis Base Nucleofugality Parameter, N^F_B, and Its Application in an Analysis of MIDA-Boronate Hydrolysis Kinetics.

Taylor NP, Gonzalez JA, Nichol GS, García-Domínguez A, Leach AG, Lloyd-Jones GC. Taylor NP, et al. Among authors: leach ag. J Org Chem. 2022 Jan 7;87(1):721-729. doi: 10.1021/acs.joc.1c02729. Epub 2021 Dec 20. J Org Chem. 2022. PMID: 34928611

3

Neighbouring group participation vs. addition to oxacarbenium ions: studies on the synthesis of mycobacterial oligosaccharides.

Stalford SA, Kilner CA, Leach AG, Turnbull WB. Stalford SA, et al. Among authors: leach ag. Org Biomol Chem. 2009 Dec 7;7(23):4842-52. doi: 10.1039/b914417j. Epub 2009 Sep 21. Org Biomol Chem. 2009. PMID: 19907773

4

Furanyl cyclic amines: a diastereoselective synthesis of 2,6-syn-disubstituted piperidines under thermodynamic control.

O'Brien M, Leach A, Armstrong RJ, Chong K, Sheridan R. O'Brien M, et al. Org Biomol Chem. 2012 Mar 28;10(12):2392-4. doi: 10.1039/c2ob07008a. Epub 2012 Feb 20. Org Biomol Chem. 2012. PMID: 22349413

5

The mechanism and regioselectivity of the ene reactions of nitroso compounds: a theoretical study of reactivity, regioselectivity, and kinetic isotope effects establishes a stepwise path involving polarized diradical intermediates.

Leach AG, Houk KN. Leach AG, et al. Org Biomol Chem. 2003 Apr 21;1(8):1389-403. doi: 10.1039/b300285c. Org Biomol Chem. 2003. PMID: 12929670

6

The origins of noncovalent catalysis of intermolecular Diels-Alder reactions by cyclodextrins, self-assembling capsules, antibodies, and RNAses.

Kim SP, Leach AG, Houk KN. Kim SP, et al. Among authors: leach ag. J Org Chem. 2002 Jun 14;67(12):4250-60. doi: 10.1021/jo011180d. J Org Chem. 2002. PMID: 12054961

7

Shapes of antibody binding sites: qualitative and quantitative analyses based on a geomorphic classification scheme.

Lee M, Lloyd P, Zhang X, Schallhorn JM, Sugimoto K, Leach AG, Sapiro G, Houk KN. Lee M, et al. Among authors: leach ag. J Org Chem. 2006 Jul 7;71(14):5082-92. doi: 10.1021/jo052659z. J Org Chem. 2006. PMID: 16808494

8

A mechanistic proposal for the protodeboronation of neat boronic acids: boronic acid mediated reaction in the solid state.

Noonan G, Leach AG. Noonan G, et al. Among authors: leach ag. Org Biomol Chem. 2015 Mar 7;13(9):2555-60. doi: 10.1039/c4ob02543a. Org Biomol Chem. 2015. PMID: 25604694

9

Transition states and mechanisms of the hetero-Diels-Alder reactions of hyponitrous acid, nitrosoalkanes, nitrosoarenes, and nitrosocarbonyl compounds.

Leach AG, Houk KN. Leach AG, et al. J Org Chem. 2001 Jul 27;66(15):5192-200. doi: 10.1021/jo0104126. J Org Chem. 2001. PMID: 11463273

10

In Situ Studies of Arylboronic Acids/Esters and R₃SiCF₃ Reagents: Kinetics, Speciation, and Dysfunction at the Carbanion-Ate Interface.

García-Domínguez A, Leach AG, Lloyd-Jones GC. García-Domínguez A, et al. Among authors: leach ag. Acc Chem Res. 2022 May 3;55(9):1324-1336. doi: 10.1021/acs.accounts.2c00113. Epub 2022 Apr 18. Acc Chem Res. 2022. PMID: 35435655 Free PMC article.

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