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Swainsonine, an alpha-mannosidase inhibitor, may worsen cervical cancer progression through the increase in myeloid derived suppressor cells population.
Silveira CRF, Cipelli M, Manzine C, Rabelo-Santos SH, Zeferino LC, Rodríguez Rodríguez G, de Assis JB, Hebster S, Bernadinelli I, Laginha F, Boccardo E, Villa LL, Termini L, Lepique AP. Silveira CRF, et al. Among authors: lepique ap. PLoS One. 2019 Mar 6;14(3):e0213184. doi: 10.1371/journal.pone.0213184. eCollection 2019. PLoS One. 2019. PMID: 30840689 Free PMC article.
The role of inflammation in HPV carcinogenesis.
Boccardo E, Lepique AP, Villa LL. Boccardo E, et al. Among authors: lepique ap. Carcinogenesis. 2010 Nov;31(11):1905-12. doi: 10.1093/carcin/bgq176. Epub 2010 Sep 5. Carcinogenesis. 2010. PMID: 20819779 Review.
Local and systemic immunomodulatory mechanisms triggered by Human Papillomavirus transformed cells: a potential role for G-CSF and neutrophils.
Alvarez KLF, Beldi M, Sarmanho F, Rossetti RAM, Silveira CRF, Mota GR, Andreoli MA, Caruso EDC, Kamillos MF, Souza AM, Mastrocalla H, Clavijo-Salomon MA, Barbuto JAM, Lorenzi NP, Longatto-Filho A, Baracat E, Lopez RVM, Villa LL, Tacla M, Lepique AP. Alvarez KLF, et al. Among authors: lepique ap. Sci Rep. 2017 Aug 21;7(1):9002. doi: 10.1038/s41598-017-09079-3. Sci Rep. 2017. PMID: 28827632 Free PMC article.
HPV-Mediated Resistance to TNF and TRAIL Is Characterized by Global Alterations in Apoptosis Regulatory Factors, Dysregulation of Death Receptors, and Induction of ROS/RNS.
Cabeça TK, de Mello Abreu A, Andrette R, de Souza Lino V, Morale MG, Aguayo F, Termini L, Villa LL, Lepique AP, Boccardo E. Cabeça TK, et al. Among authors: lepique ap. Int J Mol Sci. 2019 Jan 8;20(1):198. doi: 10.3390/ijms20010198. Int J Mol Sci. 2019. PMID: 30625987 Free PMC article.
Lactate secreted by cervical cancer cells modulates macrophage phenotype.
Stone SC, Rossetti RAM, Alvarez KLF, Carvalho JP, Margarido PFR, Baracat EC, Tacla M, Boccardo E, Yokochi K, Lorenzi NP, Lepique AP. Stone SC, et al. Among authors: lepique ap. J Leukoc Biol. 2019 May;105(5):1041-1054. doi: 10.1002/JLB.3A0718-274RR. Epub 2019 Feb 27. J Leukoc Biol. 2019. PMID: 30811636
43 results